Klinefelter syndrome is an additional X chromosome in the cells affecting males. Meiotic nondisjunction is the major result of this syndrome. There are differences in the degree of severity of physical‚ language‚ and behavioral development symptoms between affected individuals. Klinefelter syndrome is not passed from parent to child; even though‚ women who have pregnancies after the age of 35 may have an increased chance of having a boy with the presence of extra sex chromosome. Tests for chromosome
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The first published report of a man with a 47‚XYY chromosome constitution was by Dr. Avery A. Sandberg‚ et al. in 1961. It was an incidental finding in a normal 44-year-old‚ 6 ft. [183 cm] tall man of average intelligence. [edit] Effects [edit] Physical traits XYY syndrome typically causes no unusual physical features or medical problems. Males with this syndrome may be slightly taller than average and are typically a few centimeters taller than their father and siblings. Skeletal malformations
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Jacob’s Syndrome Jacob’s Syndrome is a rare chromosomal genetic syndrome where the male has an extra Y male chromosome and ends up having 47 chromosomes with XYY instead of normal 46‚XY (male) or 46‚ XX (female.) It is very rare and happens in only about 1 out of 1‚000 men. The exact reason for this is unknown. In a very rare cases it was passed from father to son‚ but in most cases it is not hereditary. It was first discovered by Patricia Jacobs in 1965. She proposed the suggestion that the
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Stickler’s Syndrome Stickler’s Syndrome is a connective tissue disorder that causes problems with vision‚ hearing‚ bones‚ and joints. Stickler’s Syndrome was named after Dr. Gunnar B. Stickler. In 1960‚ a 12 year old boy was analyzed at Mayo Foundation in Minnesota. The boy had expansions of quite a few of the joints‚ he was also very short sighted. His mother also had a problem‚ she was blind. Dr. Stickler founded that other members of this family had similar symptoms. This made Stickler
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different chromosomal disorder in humans “GENERAL GENETICS” ASSIGNMENT NO 1 Submitted to: Sir Yasir Waheed Submitted by: Aimen Arshad Submission date: 12.7.13 1. Turner syndrome: (X instead of XX or XY). In Turner syndrome‚ female sexual characteristics are present but underdeveloped. People with Turner syndrome
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Abstract Down syndrome‚ also known as trisomy 21‚ is the most common chromosome abnormality in humans and it occurs in all races. Approximately 1 of every 691 babies born in the United States each year is born with this genetic condition. Because people with Down syndrome have extra copies of genes on chromosome 21‚ the course of normal development is disrupted and this leads to the distinctive physical characteristics and other health issues that are associated with this syndrome. With appropriate
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XYY Syndrome‚ Jacob Syndrome XYY Syndrome‚ better known as the Jacob Syndrome is a rare genetic disorder which affects males due to an extra Y chromosome. Healthy males have 46 chromosomes including one X and one Y chromosome. Men with XYY syndrome have 47 chromosomes‚ two of which are Y chromosomes. It is not known why the extra Y chromosome occurs. The disorder is present at birth and is estimated to occur in one out of every one thousand live births (1). In very rare instances‚ the syndrome
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Turner Syndrome is a genetic disorder that effects development in women‚ per TurnerSyndrome.Org. Women who have Turner Syndrome have one X Chromosome instead of two full X Chromosomes that most females are born with. One of the X chromosomes are “dropped” during Meiosis‚ when the sex cells divide to form eggs in females. It is not usually inherited. Turner Syndrome can affect the development of several body systems in those who have them. Turner Syndrome is believed to be a random error during the
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Klinefelter syndrome‚ also known as the XXY condition‚ is a term used to describe males who have an extra X chromosome in most of their cells. Instead of having the usual XY chromosome pattern that most males have‚ these men have an XXY pattern. Klinefelter syndrome is named after Dr. Henry Klinefelter‚ who first described a group of symptoms found in some men with the extra X chromosome. Even though all men with Klinefelter syndrome have the extra X chromosome‚ not every XXY male has all of those
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Chromosomal Disorders 1. Name the condition. Edwards Syndrome (or Trisomy 18) 2. Outline the chromosomal abnormality. Trisomy 18‚ or Edwards syndrome‚ occurs when a person has a third copy of material from chromosome 18 instead of the usual two copies. 3. What chromosomes are involved? Chromosome 18 is the only chromosome involved with this disorder. 4. What does it affect? The majority of children born with Edward ’s syndrome appear both fragile and weak; many are underweight. Their
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