Sickle cell anemia is a genetic disease that affects the shape and functionality of red blood cells. It is caused by a mutation in the DNA of the protein‚ hemoglobin‚ specifically in the beta chain. There are 531 base pairs in this DNA strand. Substitution or point mutation occurs‚ causing “GAG” to become “GTG”. This results in valine being created instead of glutamate. The mutation causes the hemoglobin to cling together in low oxygen levels and the red blood cell changes shape‚ preventing it from
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Sickle Cell Anemia first came into the view of the world around 1910 when Dr. James Herrick; a cardiologist‚ had a patient who complained of pain and described symptoms that sounded like anemia. He handed the case down to his assistant who‚ after taking a blood sample‚ discovered that the patient’s blood cells were not shaped like normal blood cells. When the patient’s blood cells were compared to normal blood cells‚ they appeared to be “sickle shaped”. After seeing this for himself Dr. Herrick took
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g/dL for men A low hemoglobin level is called anemia‚ which can indicate a variety of serious medical conditions that may require immediate treatment. * More than 2 billion people worldwide are anemic. * Iron Deficiency Anemia (IDA) accounts for at least half of all anemia cases worldwide. * Causes almost 1 million deaths a year. * Recognized as a top-ten contributing factor to the global burden of disease. Types and Causes Anemia can be chronic (consistently low hemoglobin levels)
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Background One of the most extensive nutritional deficiencies is iron deficiency. Globally >2 billion people are suffering from iron-deficiency anemia. Iron is the mineral found in every cell of the human body. [1] During blood loss‚ inadequate iron intake‚ pregnancy and poor absorption of iron the human body suffers a condition called iron deficiency anemia. According to the Office of Dietary Supplements it is declared that iron needs vary by gender and by age. Infants need atleast 11mg/day while
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Differential diagnose 1: Sickle Cell Anemia A 17-year-old African American female presented to the clinic with the following symptoms‚ chest and abdominal pain‚ and jaundice eyes. Her vital signs revealed B/P 98/50‚ pulse 112‚ respiration. 28 and temp. 99.9. EKG and chest x-ray completed with the result within normal range. She was discharged‚ and within four hours returned to the ER. Sickle cell disease is defined as a group of heredity disorder characterized by abnormal hemoglobin‚ called hemoglobin
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Though participating in three back-to-back sports in high school is exhilarating and entertaining‚ it can have many negative effects. For instance‚ running cross country‚ playing soccer‚ and running track back-to-back has had serious effects on a particular athlete. After participating in these three sports for about a year and a half‚ this athlete began to notice the effects during the second year of track. First‚ symptoms like fatigue and dizziness and loss of endurance appeared‚ but she blamed
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eats only pasta‚ breads‚ and hot dogs‚ and she drinks only artificial fruit punch. Lily has iron deficiency anemia. Infants can be infected from the time of birth from certain forms of anemia. Certain forms of anemia are hereditary. When girls are not getting the proper amount of iron in their diet then they may become iron deficiency. There are many different symptoms of iron deficiency anemia but the most common are swelling of the tongue‚ drying of the lips‚ and eating and craving ice. Lily’s mother
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Congenital Spherocytic Anemia‚ also known as Hereditary Spherocytosis is a rare blood condition I have had since my birth and this is why I wanted to research it. A lot of people have a hard time understanding what this condition is and what effects it has on a person; it requires a lot of in depth information to get a full understanding. Hereditary Spherocytosis is a red blood cell disorder which changes the shape of the cells to be spherical‚ which causes a lot of complications. The Outcome was
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Drug study Sangobion: Anti emetic Indications : Anemia Moa: It replenishes iron stores in the body and corrects hemoglobin deficit by increasing hemoglobin levels A/E: GI upset NC: Administer with meals‚ teach client breathing techniques‚ monitor hemoglobin count. Domepridone : Motillium (anti dopamionergic) Indications: patient has gastric tube Moa: Stimulates gastrointestinal by acting as a competitive antagonist at dopamine D2 receptor‚ inhibits gastrointestinal motility‚ reduces
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References: Agency for Healthcare Research and Quality (2003). Prolonged bottle feeding of young children may lead to childhood obesity and iron deficiency anemia. Research Activities‚ 270‚ 6. American Academy of Pediatric Dentistry (1999). Oral health policies. Pediatric Dentistry‚ 21‚ 18-37 (http://www.aapd.org). American Academy of Pediatrics‚Committee on Nutrition (1998). Pediatric nutrition handbook‚ 4"^
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