Genetics of Sickle Cell Anemia Objectives • To observe how a disease can act as a selective force • To describe changes in allele frequencies in a population as a result of a selective force Hypothesis The starting ratio of HbA to HbS is 3:1; in a typical population‚ the Homozygous Dominant Gene would become the standard‚ but because carrying the Heterozygous version of the allele has an advantage to fighting Malaria it will become the dominant Allele for the population. The HbA/HbS gene will
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Iron Deficiency Anemia Imagine that you lived your life to the fullest potential‚ while not having a single idea that a heart attack was right around for you. You are exhausted and have unusual cravings for ice even when you’re freezing and cannot get warm. On top of that‚ you cannot explain why you are having a shortness of breath or foggy thinking. If you imagine your life like this‚ then you are living with a condition called iron deficiency anemia. IDA is a common type of anemia‚ a condition in
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LABORATORY REPORT PRACTICAL 2 (ELECTROPHORESIS OF SERUM PROTEIN) DATE : 10 OCTOBER 2013 PART A SEPARATION OF SERUM PROTEINS USING THE ELECTROPHORESIS METHOD. OBJECTIVES: 1. To understand the analytical methods involved in analyzing serum proteins. 2. To study the serum protein electrophoresis pattern to aid the understanding of the relationship between the structure and the function of proteins. PRINCIPLE OF PRACTICAL: This technique is based on the movement of
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sickle cell anemia can make a person more resistant to contracting malaria If it had not been for Anthony Allison‚ the world as we know it today would drastically change. Like the video stated‚ many people with the sickle cell anemia would meet “death before adulthood”. Areas with high frequencies of anopheles mosquito and sickle cell anemia would correlate but nobody would understand why. I admire Allison for not only having the burning inquiry to determine why the sickle cell anemia character was
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Evolution of Disease Sickle Cell Anemia Sickle Cell Anemia is a disease that which the red blood cells form an abnormal sickle or crescents shape. Red blood cells are very important to the human body because they carry oxygen throughout the body. The main causes of Sickle cell is when the cells in the body mutate into abnormal cell called haemoglobin S. Haemoglobin S causes the red blood cells to become sickle shaped‚ rigid. This causes to make it more difficult for the cells to flow the vein
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Sickle cell anemia was first discovered in the year of 1910. A young man by the name Walter Clement Noel from the island of Grenada‚ studied in Chicago. He went to Dr. James B. Herrick‚ whom was a cardiologist‚ with symptoms of anemia‚ who assigned Dr. Ernest Irons to the case. There Dr. Irons noticed that Noel’s red blood cells were the shape of a sickle. Although sickle cell anemia has occurred in Africa for thousands of years‚ Dr. Herrick was the first to provide a formal description of sickle
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Sickle cell anemia (SCA) is a genetic disorder that is hereditary. It affects the blood‚ and is caused when the hemoglobin in blood cells are deprived in oxygen from the proteins. These cause normal round blood cells‚ to have are rigid sickle shape. People affected by SCA have a higher risk of death‚ stroke‚ severe attacks‚ and severe rushes of pain. James Herrick discovered an anemia‚ and found bizarre sickle-shaped cells in 1910. A treatment for the disease was discovered in the 1920s by E. Vernon
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SICKLE CELL ANAEMIA Sickle cell anemia is an inherited condition. People with sickle cell anemia inherit two copies of the sickle cell gene‚ one from each parent. The sickle cell gene makes abnormal hemoglobin called Hemoglobin-S. The sickle cell gene is a trait due to a change in ONE nucleotide in the DNA sequence that leads to a change in ONE amino acid that changes how the hemoglobin protein folds. This change in the structure of the hemoglobin protein leads to a change in the shape of
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Sickle Cell Anemia Sickle Cell Anemia occurs in about 1 out of 500 African American births‚ and 1 out of 36‚000 Hispanic births. It is a lifelong disease‚ and sometime can be deadly. According to Dr. Whittaker‚ in our region there are abnormally higher cases of Sickle Cell Anemia‚ so I found it important to learn more about the disease‚ what cause it‚ what are the symptoms as well as the options of treatments for this disease. According to www.invista.com‚ it is believed that sickle cell disease
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Sickle Cell Anemia "An ISU student died March 12 from complications of Sickle Cell Anemia there is no cure for Sickle Cell Anemia" (Indiana Statesman‚ 2004). What is Sickle Cell Anemia? According to National Institute of Health‚ Sickle Cell Anemia is a lifelong‚ inherited blood disorder or disease‚ characterized primarily by chronic anemia and periodic episodes of pain. It is one form of sickle cell disease‚ a category of blood disorders caused by defective hemoglobin. Hemoglobin is a substance
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