The androgen receptor on prostate cancer cells is a nuclear receptor that is essential for cell growth and survival. As well‚ AR signalling contributes to metastasis by facilitating EMT. Advanced prostate cancers are initially treated with hormone deprivation therapies to curb prostate cancer progression‚ however the efficacy is limited to 2-3 years before cancer progresses to castration resistant prostate cancer (CRPC). In CRPC‚ the androgen receptor signalling pathway has
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Developmental psychology deals with the lifelong process of change and it is the study of how and why people change over time in the way they behave‚ think and relate to others. More specifically‚ identity development‚ such as the formation of gender roles‚ is influenced by biological‚ cognitive‚ and social factors to a great extent‚ since it is impossible and unfitting to attribute one such factor to the development these roles society has deemed. There has long been controversy about the relative
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unknown. However‚ medically the cause is believed to be genetical and hormonal problems. A few polycystic ovarian women will be less sensitive to Insulin and this condition is called Insulin resistance. It stimulates ovaries to produce male hormones “Androgen”
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“Are We Born With Our Sexual Identity or Do We Choose It?” Sociology research paper Are you born with your sexual identity or do you choose it ? Identifying your sexual identity comes from a very young age. It starts when you first discover your genitals at months of you being born. Then you chose whether you want to play with stereotyped toys that are identified for boys or girls. After that‚ you learn gender role behavior‚ where you either do things “that boys do” or “that girls do”. Another
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men are taller‚ heavier and more muscular than the average women. Specifically the authors mention that researches have speculated that certain behavioral differences are due to male and female hormones. Both men and women produce the male hormone androgen and the female hormone estrogen but in different quantities. The physical development is due to the hormone who signals the embryo to develop as a male with male body shape and sexual organs. The prediction of a research made by rose‚ Gordon and
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Acne‚ Pimples - Causes‚ Treatment What is Acne or Pimples ? Acne (also known as Pimples) is a skin problem that affects almost all teenagers. The condition results from the action of hormones on the skin’s oil glands (sebaceous glands). The sebaceous glands make an oily substance called sebum that empties onto the skin surface through the hair follicle opening (pore). The mixture of oil and cells allows bacteria that normally live on the skin to grow in the follicle openings. When this happens
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changes. These powerful chemicals‚ known as hormones‚ are secreted by the endocrine glands and carried through the body by the bloodstream (Santrok‚ 2007). Two important hormones play functional roles: androgens for male and estrogen for female. Testosterone‚ also known as an androgen‚ plays an important role in male pubertal development such as‚ development of external genitals‚ an increase in height‚ and voice change‚ as well as sexual desire and activity (Santrok‚ 2007). Estradiol‚
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recognize that he has more features of a male than of a female‚ physically. Although his genitals may look abnormal‚ he still has other features of a male. Part 2 1. According to the nature view of psychosexual differentiation‚ prenatal exposure to androgen could influence the development of gender identity. David’s experience did not support the nurture theory. None of his characteristics supported the nurture theory. David being neat and tidy was not a feminine characteristic but rather one that was
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determine one’s gender. Gender is influenced at a pre-natal stage‚ via the release of testosterone from the gonads of an XY foetus. It is this testosterone release that sets in motion the train of events that lead to the eventual release of the other androgens from the pituitary gland. It is the lack of testes‚ and therefore the lack of testosterone‚ that influences an XX foetus to develop into a female. Even before these events take place‚ the undeveloped gonads in the XX or XY foetus (Mullerian and
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doctors believe that the cause behind PCOS is genetics and hormonal imbalances. Androgen‚ a male hormone‚ is also produced by females in a very insignificant amount. If they starts to produce Androgen in a more than normal manner‚ then it may cause PCOS and therefore‚ affects the development and release process of eggs during ovulation which consequently leads towards infertility. This more than normal amount of androgen may be a result of high insulin. Therefore‚ we can consider high insulin as a
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