Analgesics Using the thin layer chromatography the major components of a commercial analgesic tablet will be indentified and purified. The active ingredients of the analgesic used were characterized by comparison with chromatograms of aspirin‚ acetaminophen‚ ibuprofen‚ mefanemic acid‚ and caffeine through the use of UV chromatography then the Rf value was calculated for each solvent. INTRODUCTION In this experiment‚ thin-layer chromatography (TLC) will be used to determine the composition
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DATRIL: PIONEERING THE ACETAMINOPHEN MARKET Decision Marvin Koslow‚ vice president for marketing services at Bristol-Myers is going to choose a positioning strategy for Datril‚ an acetaminophen based analgesic‚ in order to solidify Bristol-Myers’ position in the analgesics market and gain share in the rapidly growing acetaminophen market. There are two possible options: ‘Pricing at par with Tylenol and it as a Tylenol substitute‚ featuring Bristol-Myers product’ and ‘low Priced alternative to Tylenol’
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Response for Case Datril 1) What course of action should Datril take? It should solidify its position in the analgesic market and gain share in the rapidly growing acetaminophen market. It should target both Tylenol Users and Aspirin Users. On one hand‚ it should explain to customers that Datril’s effect is identical to Tylenol and use low-price promotion. On the other hand‚ it should leverage Bristal-Myers’s name to facilitate its market penetration. Generally‚ it should focus on advertisement
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over-the-counter classifications of painkillers are acetaminophen‚ nonsteroidal anti-inflammatory drugs (NSAIDs)‚ and salicylates. One of the most popular over-the-counter drugs used to relieve pain is Tylenol. Tylenol is the brand name for acetaminophen or paracetamol. Consumers take acetaminophen to relieve mild to moderate pain such as for osteoarthritis or headaches. The National Center for Biotechnology Information (NCBI) says that acetaminophen works by changing the way the body senses pain (2012)
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prepared by reacting salicylic acid with acetic anhydride:  Figure 1. Chemical Equation for Aspirin Synthesis (Aspirin) Tylenol‚ acetaminophen‚ is also used both as a fever reducer and pain reliever. Acetaminophen is prepared by reacting ammonia with acetic acid:  Figure 2. Chemical Equation for Tylenol Synthesis (Acetaminophen) The purity of an aspirin or Tylenol sample can be obtained by determining the melting point. The presence of impurities always lowers the melting
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in 24 hours” and “adults and children 12 years of age and over: 2 caplets every 6 hours while symptoms persist”. (Benadryl) So what happened in this case? Acetaminophen is an active ingredient in Benadryl® Maximum Strength Severe Allergy and Sinus along with Diphenhydramine and Pseudoephedrine. In each capsule‚ there is 500 mg of acetaminophen‚ therefore the is 1000 mg in one dose‚ and 4000 mg
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------------------------------------------------- Drug Name: Hydrocodone/Acetaminophen Trade Name: Vicodin ------------------------------------------------- Indication: Relief of moderate to severe pain ------------------------------------------------- Safe Range: Peds: <40kg 0.2mg/kg-15mg/kg/dose q3-4h PRN. Maximum dose of acetaminophen 1000 mg/dose and 4000mg/day; Adult initially 10mg q3-4h PRN. ------------------------------------------------- Action / Where does it
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where the given distance from origin to solvent front measures 59 mm: 1.) acetaminophen has a Rf value of 0.48; 2.) aspirin has a Rf value of 0.64; 3.) caffeine has a Rf value of 0.22; 4.) Biogesic® sample has a Rf value of 0.48 ; 5.) ibuprofen has a Rf value of 0.73; and 6.) mefenamic Acid has a Rf value of 0.76. Thus‚ the study shows that by having equal Rf values of about 0.48‚ Biogesic®’s most active component is acetaminophen (paracetamol)‚ a relatively polar compound having a molecular formula
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through melting point‚ percent recover‚ and Rf values. The comparable data for acetaminophen from the manufacturer is 500mg of active ingredient. After conducting the experiment-extraction‚ distillation‚ and evaporation- 451mg of active ingredient. This relates to a 68.1% recovery. The melting point was between 158 and 165 degrees Celsius‚ which is almost ten degrees lower than the published melting point of acetaminophen. After conducting a TLC plate‚ the Rf value was calculated to be .4268‚ the same
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Organic Chemistry Lab Introduction: Panacetin purportedly includes sucrose‚ aspirin‚ and acetaminophen. However‚ the accuracy of Panacetin’s contents has been called into question by the Association for Safe Pharmaceuticals. Therefore‚ the lab must discover the accuracy of the ingredients listed on Panacetin’s label. The unknown in this experiment is presumed to be something similar to acetaminophen‚ such as acetanilide or phenacetin. Recrystallization and melting point temperature were
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