Cystic fibrosis is caused by a mutated gene‚ cystic fibrosis transmembrane conductance regulator. It’s a disease that changes the way your body makes mucus and sweat. It also changes how well your lungs‚ digestive system‚ and other body parts work. Cystic fibrosis causes your mucus to be too thick‚ or sweat to be too salty. Mucus that is too thick causes your lungs to clog and makes it hard to breathe. It can block your pancreas‚ so you can’t digest your food very well. I believe that cystic fibrosis
Premium Cystic fibrosis
Stem cells – the cure to Cystic Fibrosis? Cystic Fibrosis is one of the UK’s most common life threatening diseases with it affecting over 9‚000 people. Statistics show that one in twenty five people in the UK carry the faulty gene‚ each week five babies are born with the disease and another two young lives are lost. Cystic Fibrosis is a genetic disorder caused by a recessive allele. It affects the internal organs‚ especially the lungs and digestive system‚ by clogging them with thick sticky mucus
Premium Cell Stem cell Bone marrow
Cystic fibrosis is a disease passed down through families‚ a genetic disorder‚ that causes thick‚ sticky mucus to build up in the lungs‚ digestive tract‚ and other areas of the body. Cystic fibrosis is where it affects the cells that produce mucus‚sweat and digestive juices. These fluids are normally thin and slippery‚ but in Cystic fibrosis‚ a defective gene causes the fluids to become thick and sticky plugging up tubes‚ ducts and passageways in the human body especially in the lungs and pancreas
Premium Cystic fibrosis Genetics Bacteria
Cause of Cystic Fibrosis Cystic Fibrosis is caused by a mutation in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. The CFTR gene codes for the CFTR protein which is a chloride ion channel belonging to the ABC (what does it stand for) transporter superfamily of proteins. The CFTR proteins are normally located on the apical plasma membrane of epithelial cells in the airways‚ lungs‚ skin‚ digestive organs (E.g. - the pancreas and intestine) and reproductive tracts (E.g. - sperm
Premium Cystic fibrosis DNA Protein
throughout their life. Some of which are inherited from their parents‚ they develop at birth or during their adulthood. Some of these mutations are harmless and can go unnoticed for your whole existence‚ while others can alter your health drastically. There are some mutations that are considered to be valuable‚ as well as a silent one which does not affect you at all. The mutations heard about most often are those that cause disease such as‚ cystic fibrosis‚ sickle cell disease‚ and Tay-Sachs disease (Genetics
Premium DNA Genetics Gene
Cystic Fibrosis‚ commonly known as CF‚ is a genetic disorder that causes the body to overproduce mucus. The overproduction of mucus affects many parts of the body. Primarily the lungs‚ pancreas‚ reproductive system‚ liver‚ sweat glands and intestines are all affected by the condition (Falvo 485). CF is most prevalent in Caucasians‚ but it also is seen in African Americans‚ Hispanics and Native Americans (“Cystic Fibrosis” 2012). Millions of people are carriers of the CF gene but in order for a
Premium Cystic fibrosis Lung Asthma
that encodes for a chloride channel called the cystic fibrosis transmembrane conductance regulator (CFTR). In ductal epithelial cells‚ CFTR is highly expressed and functions to transport fluid and anions into the lumen. Dysfunction of the CFTR gene leads to a decrease in luminal fluid volume and decreased pH‚ resulting in protein precipitation within the ductal lumen and loss of normal acinar cell function. Estimated gene frequency of cystic fibrosis varies in different ethnic groups with highest
Premium Obesity Diabetes mellitus Hypertension
Describe the symptoms of cystic fibrosis. The different symptoms of cystic fibrosis include repeated infections and thick mucus secretions in the lungs‚ it affects you with wheezing‚ a chronic cough‚ bronchitis‚ asthma‚ weight loss‚ dehydration‚ and many more mainly affecting the lungs and stomach. Sufferers may also feel very fatigued easily. 2. Describe two problems associated with the presence of thick‚ sticky mucus (a) in the lungs and breathing passageways (b) in the digestive system
Premium Asthma Cystic fibrosis Pneumonia
Cystic fibrosis is an inherited disease of secretory glands‚ including the glands that make mucus and sweat. "Inherited" means that the disease is passed through the genes from parents to children1‚ 2. People who have cystic fibrosis inherit two faulty cystic fibrosis genes one from each parent. The parents likely don’t have the disease themselves. Cystic fibrosis mostly affects the lungs‚ pancreas‚ liver‚ intestines‚ sinuses‚ and sex organs. Mucus is a substance made by the lining of some body tissues
Premium Immune system Bacteria Blood
History of Cystic Fibrosis “Woe to that child which when kissed on the forehead tastes salty. He is bewitched and soon must die.” This proverb‚ dating back to European folklore in the 1700’s‚ was the diagnosis for the disease recognized today as Cystic Fibrosis (CF). In that time period the disease was usually fatal and common among infants. The excessive salt in the sweat‚ just one symptom of CF‚ made the disease identifiable. However‚ since the time of European folklore‚ various renowned scientists
Premium Cystic fibrosis Gene DNA