Preview

Whooping Cough: Bordetella Pertussis And Parapertussis

Good Essays
Open Document
Open Document
99 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Whooping Cough: Bordetella Pertussis And Parapertussis
Whooping cough, also known as pertussis, is characterized by paroxysmal cough with or without whoops, leukocytosis, hypoglycemia, histamine sensitivity, immobilization and/or damage of the cilia of the ciliated epithelium of the respiratory tract, alveolitis and bronchopneumonia. Bordetella pertussis and parapertussis is the bacterium responsible for “whooping cough”. Both have caused outbreaks in humans and produce similar virulence factors. B. pertussis and parapertussis are closely related species and it has been well documented by DNA hybridization studies. Although both species produce a number of characterized virulence factors, only B. pertussis produces the well-characterized pertussis toxin (PTX). B. parapertussis carries the
Continue Reading
View Writing Issues

You May Also Find These Documents Helpful

  • Powerful Essays

    Med Micro Unknown Report Bordetella Pertussis
    • 1347 Words
    • 6 Pages

    Med Micro Unknown Report Bordetella Pertussis

    The air is a complex mixture of dust, sediment, and airborne pathogens. Case study 49 dealt with the identification of unknown harmful pathogens that inhabit the upper respiratory tract. Haemophilus species, Bordetella species, and Corynebacteria diphtheria are common causative agents of upper respiratory illness and served as a lead for this investigation.…

    • 1347 Words
    • 6 Pages
    Powerful Essays
    Read More
  • Good Essays

    Whooping Cough Research Paper
    • 1113 Words
    • 5 Pages

    Whooping Cough Research Paper

    Pertussis is a respiratory tract infection that is very contagious. It got its name because of the sharp high-pitched intake of air that makes a “whooping” sound that follows a fit of coughs. It was originally considered a childhood disease but now it affects those children that are too young to have completed vaccination and those who have slowly lost the immunity to it. This can cause death in infants, which is why pregnant women should be vaccinated against it. Whooping cough is caused by the bacteria called Bordetella pertussis. It produces many virulence factors including the pertussis toxin and since it can be transmitted through droplets, it can go from person to person making it highly contagious. When the infected person coughs or sneezes, the droplets in the air can be taken in by anyone nearby.…

    • 1113 Words
    • 5 Pages
    Good Essays
    Read More
  • Good Essays

    Bordetella Pertussis Research Paper
    • 1991 Words
    • 8 Pages

    Bordetella Pertussis Research Paper

    It is often thought that whooping cough is an outdated disease, due to the many ways we now have to combat the pathogen, but every year almost 400,000 people die due to infection with Bordetella pertussis (1, 41). Bordetella pertussis is a gram-negative coccobacillus bacterium, which causes whooping cough in humans (1, 41). The bacterium is spread by air borne particles or mucus droplets and is highly contagious. Although there is no known reservoir for the pathogen humans can often be asymptomatic, due to vaccination or immunity, and can easily spread the disease from person to person through coughing or sneezing (1, 41). Once inhaled the pathogen enters the respiratory tract and attaches to the ciliated respiratory epithelium. There…

    • 1991 Words
    • 8 Pages
    Good Essays
    Read More
  • Good Essays

    RE: M4D1
    • 466 Words
    • 2 Pages

    RE: M4D1

    Koch was the first scientist to prove that bacteria actually cause disease. He scientifically demonstrated that a disease is caused by a particular organism. He created four general guidelines to aid in identification of disease causing pathogens. These guidelines developed from his work with purified cultures of anthrax that had been isolated from dead animals. Koch also proved that the same disease could be passed from one organism to another. Pasteur proved that microorganisms could be present in non-living matter. Bassi preceded both Pasteur and Koch in the discovery that many diseases of both man and animal were caused by parasites. This was vital in the formulation of the germ theory, to which both Pasteur and Koch would later expound. Bassi and Pasteur, though their research was important to later research, did not discover the true cause of disease, nor were they able to isolate the causal organisms. Koch was not only able to isolate the causal pathogen, he was able to correlate a specific pathogen caused a specific disease. We use his postulates because, if followed, they provide accurate data.…

    • 466 Words
    • 2 Pages
    Good Essays
    Read More
  • Powerful Essays

    Borrelia Burgdorferi: Lyme Disease
    • 3728 Words
    • 15 Pages

    Borrelia Burgdorferi: Lyme Disease

    The outer membrane of Borrelia burgdorferi is composed of various unique outer surface proteins (Osp) and are thought to play a role in virulence. Osp A and Osp B are by far the most abundant outer surface…

    • 3728 Words
    • 15 Pages
    Powerful Essays
    Read More
  • Good Essays

    Whooping Cough in Maricopa County
    • 874 Words
    • 4 Pages

    Whooping Cough in Maricopa County

    Whooping cough is a communicable disease. Due to the nature of whooping cough being highly contagious, an outbreak of the disease can be serious and affect a large amount of people in a…

    • 874 Words
    • 4 Pages
    Good Essays
    Read More
  • Good Essays

    Whooping Cough
    • 1034 Words
    • 5 Pages

    Whooping Cough

    Pertussis is a highly contagious bacterial disease that causes uncontrollable, violent coughing. The coughing can make it hard to breathe. A deep "whooping" sound is often heard when the patient tries to take a breath.…

    • 1034 Words
    • 5 Pages
    Good Essays
    Read More
  • Good Essays

    Bordetella Pertussis Research Paper
    • 682 Words
    • 3 Pages

    Bordetella Pertussis Research Paper

    Bordetella pertussis is the cause of pertussis which is also known as whooping cough. It is a gram negative pleomorphic bacillus. Pertussis is highly contagious and can be deadly to newborn infants because they do not have the immunity to protect against this disease. Every year there are outbreaks of pertussis especially in the high school age children, even though most have had the Tdap (tetanus, diphtheria and acellular pertussis) Vaccine. Humans are the only host to the Bordetella pertussis bacterium and are spread by droplets, especially when the infected individual is having spasmodic coughing.…

    • 682 Words
    • 3 Pages
    Good Essays
    Read More
  • Good Essays

    Whooping Cough Vaccine Research Paper
    • 392 Words
    • 2 Pages

    Whooping Cough Vaccine Research Paper

    Whooping cough is very contagious and is a severe threat for babies. People with whooping cough usually spread the disease by coughing or sneezing while in close contact with others, then breathe in the bacteria and causes the disease. Many babies who get whooping cough are infected by parents, siblings, or other people that have it. If you are pregnant, get vaccinated in your third trimester .Surround your baby with vaccinated family members and caregivers. Make sure your baby gets his all doses of his whooping cough vaccine. Pregnant Women need a Whooping cough vaccine.…

    • 392 Words
    • 2 Pages
    Good Essays
    Read More
  • Powerful Essays

    Pertussis: Whooping Cough
    • 1469 Words
    • 6 Pages

    Pertussis: Whooping Cough

    Pertussis (Whooping cough) is an extremely contagious, respiratory disease, which is caused by the bacterium Bordetella. It is estimated that around 200 infants under the age of 6 months who contract whooping cough will die from pneumonia or brain damage. The disease is spread by airborne droplets from the upper respiratory tract (when the infected person coughs or sneezes) and is highly contagious.…

    • 1469 Words
    • 6 Pages
    Powerful Essays
    Read More
  • Good Essays

    Symptoms Of Whooping Cough
    • 151 Words
    • 1 Page

    Symptoms Of Whooping Cough

    Whooping cough is an infection that is caught by breathing in aerosolized droplets that contain the bacteria, Bordetella pertussis. The disease typically lasts anywhere from a month to almost three months. The incubation period lasts 7-21 days. Then the disease progresses through three phases. A catarrhal phase, paroxysmal phase, and convalescent phase. The symptoms of whooping cough present differently in the first two phases. The catarrhal phase presents symptoms that seem like a typical upper respiratory tract infection. However, in the paroxysmal phase presents a paroxysmal cough. This cough is a rapidly repeating cough, that sometimes causes patients to vomit. The coughing will always causes the patient to struggle taking deep breaths…

    • 151 Words
    • 1 Page
    Good Essays
    Read More
  • Good Essays

    pertussis
    • 779 Words
    • 3 Pages

    pertussis

    Pertussis has made a reemergence in well-vaccinated populations. Pathogenic adaptation and the decrease in strength are most likely the cause of the reemergence of pertussis. There is pressure for vaccine research because of the resurgence of the pathogen. Pertussis remains one of the leading causes of vaccine preventable deaths in infants under 1 year of age. Pertussis is a Gram-negative, bacillus called Bordetella pertussis. This bacterium binds to the ciliated epithelial cells in the nasopharynx of the upper respiratory tract. Disease presentation depends on age and history of previous infection or vaccination. Young infants present apnea and cyanosis, with or without disease symptoms. Adults and teens usually show mild symptoms, and have a typical prolonged cough. The human Bordetellea are classified as monomorphic, but there is evidence of genetic variation in B. pertussis. As far as vaccines, there are two types of licensed pertussis vaccines. The first generation is whole cell vaccines (WCVs), which are killed cells. The second generation is acellular vaccines (ACVs), which contain virulence factors. The WCVs contain whole dead cells that can cause more adverse effects compared to ACVs, which have been gradually replacing WCVs. Some of the virulence factors that the ACV uses are pertactin, filamentous hemagglutinin, two fimbriae serotypes, and chemically detoxified pertussis toxin. WCVs induce type 1 helper T cells, which assist cytotoxic T cells. WCVs also induce a broad antibody response against a range of surface antigens. ACVs induce type 2 helper T cells, which assist B cells. It causes a high antibody response against the vaccine antigens presented. Both of these vaccines give satisfactory long-term protection against pertussis. WCV is estimated to protect for 4-12 years and the AVC could last 5-7 years. Programs to vaccinate began in the 1950s with the WCV. This caused a dramatic drop in mortality and morbidity in children.…

    • 779 Words
    • 3 Pages
    Good Essays
    Read More
  • Powerful Essays

    Pertussis Research Paper
    • 2056 Words
    • 9 Pages

    Pertussis Research Paper

    Pertussis, also known as whooping cough, is a highly contagious respiratory tract infection of humans that is caused by a gram-negative bacterial pathogen Bordetella pertussis. These bacteria bind to ciliated cells that line the respiratory tract by obstructing their ciliary movement and killing the cells. B. pertussis can be transmitted from one person to another through respiratory droplets such as coughing, sneezing, or sharing a breathing space. B.pertussis host range can be found only in humans (sole reservoir) most especially, the adults and adolescents with an undiagnosed infection who may transmit the infection to infants and children through droplets transmission (http://wwwpublichealth.gc.ca). Pertussis is a re-emerging disease, that is, the incidence has recently been on the rise due to parents refusal to vaccinate their infants because of their belief that vaccines may not be safe, and also due to the waning immunity among vaccinated adults (Krause et al.,1992).…

    • 2056 Words
    • 9 Pages
    Powerful Essays
    Read More
  • Good Essays

    Pertussis- Essay
    • 504 Words
    • 3 Pages

    Pertussis- Essay

    More commonly known as whooping cough, Pertussis is a contagious infection of the respiratory tract caused by the bacteria Bordatella Pertussis. Thick mucus accumulates in the airways, provoking heavy coughing spells. Pertussis can be spread via droplet. The infected person may sneeze or cough and the tiny germ droplets may be inhaled by any bystander. Whooping cough was seen mostly in children before, but after the development of vaccines against it the infection is found in many teens or adults whose immunity has faded and babies. Although death from Pertussis is rare, it is important for pregnant women especially to be vaccinated against the infection.…

    • 504 Words
    • 3 Pages
    Good Essays
    Read More
  • Good Essays

    Essay On Pertussis
    • 359 Words
    • 2 Pages

    Essay On Pertussis

    The bacteria bordetella pertussis attaches to the cilia in the respiratory tract causing it to release some sort of toxin. This toxin interrupts…

    • 359 Words
    • 2 Pages
    Good Essays
    Read More

Related Topics