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Aspirin Yaletza Palafox P.6 10/31/12
Felix Hoffmann was born in Ludwigsburg, Germany, on January 21, 1868 to an industrialist father named Jakob. He went to the University of Munich and there he studied Chemistry and Pharmacy. In 1893 he graduated from there with a doctoral degree. While in 1894 he began working for the Bayer pharmaceutical research facility in Elberfeld, Germany as a chemist.
On August 10, 1897 Felix Hoffmann invented a medicine called Aspirin. It all started with this question “How will I take away the pain”. Felix Hoffmann’s father suffered from arthritis and there were a few amounts of pain relievers on the market. His father hated the taste of artificial salicylic acid which was the most reliable remedy at the time. That acid other than just having a terrible taste it also could irritate your stomach and could cause ulcers. This then inspired Felix to try and find a cure that took away or subdued an everyday pain. Felix and another researcher named Arthur Eichengrun started to investigate the records and notes that had been written by the French chemist named Charles Frederic Gerhardt. Charles had mixed acetyl chloride with sodium salicylate, but it was an unstable compound and didn’t seem to work so when Felix and Arthur studied the scientific notes on these experiments he managed to come up with a variant when he used to different ingredients. First of all he mixed a different form of salicylic acid gotten from a herb called Spirea Alba with acetic anhydride instead of acetyl chloride. This mixture was way more stable form than what Charles had done. Felix named this type of medicine acetylsalicylic acid. This medicine started being tested on animals and later on on patients. Felix gave this medicine or remedy to his arthritic who then experienced a reduction in pain. Executives at Bayer then changed the name to Aspirin. The prefix of ‘a’ signified the process of acetylation that Charles Frederic

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