The methods of testing include the draize, acute toxicity, skin irritation, skin sensitization, and dermal penetration. The draize test is a method that can cause irritation to the skin and/or eyes. The acute toxicity test is done to determine danger of exposure to a chemical by mouth, skin, or inflammation. The draize test can also cause animal convulsions, loss of motor function, and seizures. The dermal penetration test is the injection of chemicals into the bloodstream to understand skin absorption. Over the years many places around the world have prohibited testing cosmetics on animals. Experiments on animals are cruel and expensive. New scientists are developing methods that replace animals. The tests use human cells and tissue (known as in-vitro methods), computer modeling techniques (known as in-silico methods), and studies with human volunteers. The new experiments take less time and money to complete. The primary use of in-vitro tests is to detect specific toxic properties of drugs and/or chemicals. The studies normally take place in labware such as test tubes, flasks, petri dishes and microtiter plates. Studies use components of organisms that have been isolated to get a more detailed and convenient analysis that can be done with whole organisms. Results obtained from in-vitro tests may not be 100%
The methods of testing include the draize, acute toxicity, skin irritation, skin sensitization, and dermal penetration. The draize test is a method that can cause irritation to the skin and/or eyes. The acute toxicity test is done to determine danger of exposure to a chemical by mouth, skin, or inflammation. The draize test can also cause animal convulsions, loss of motor function, and seizures. The dermal penetration test is the injection of chemicals into the bloodstream to understand skin absorption. Over the years many places around the world have prohibited testing cosmetics on animals. Experiments on animals are cruel and expensive. New scientists are developing methods that replace animals. The tests use human cells and tissue (known as in-vitro methods), computer modeling techniques (known as in-silico methods), and studies with human volunteers. The new experiments take less time and money to complete. The primary use of in-vitro tests is to detect specific toxic properties of drugs and/or chemicals. The studies normally take place in labware such as test tubes, flasks, petri dishes and microtiter plates. Studies use components of organisms that have been isolated to get a more detailed and convenient analysis that can be done with whole organisms. Results obtained from in-vitro tests may not be 100%