Ubiquinone Heart Failure
Background
Heart failure (HF) is a condition in which the heart muscles lose its ability to pump sufficient blood to the body. It’s considered as one of the leading causes of death in the U.S with an estimated direct and indirect cost of $39 billion per year.1 Bioenergetics dysfunction is common in HF patients, which leads to energy starvation of the cardiac cells.2 Therefore, some medical providers encourage their patients to take ubiquinone, a lipid-soluble antioxidant, as an adjunct HF therapy. Ubiquinone, commonly known as coenzyme Q10, is required for the production of ATP in the electron transport chain, with the highest concentration in the heart muscles. It has been shown that patient with HF have reduced amount of coenzyme Q10 which
Heart failure (HF) is a condition in which the heart muscles lose its ability to pump sufficient blood to the body. It’s considered as one of the leading causes of death in the U.S with an estimated direct and indirect cost of $39 billion per year.1 Bioenergetics dysfunction is common in HF patients, which leads to energy starvation of the cardiac cells.2 Therefore, some medical providers encourage their patients to take ubiquinone, a lipid-soluble antioxidant, as an adjunct HF therapy. Ubiquinone, commonly known as coenzyme Q10, is required for the production of ATP in the electron transport chain, with the highest concentration in the heart muscles. It has been shown that patient with HF have reduced amount of coenzyme Q10 which