But before studying how stem cells can be used to restore …show more content…
Epithelium is derived from the oral ectoderm, while the only source of mesenchyme able to sustain tooth development is derived from multipotential stem cells called cranial neural crest cells (NCCs) (Jheon et al., 2013; Miletich, 2004). Some cranial NCCs located in the dental pulp, which have the unique capacity to produce mesenchymal cells that are capable of differentiating into highly specialized cell types, maintain plasticity into their postnatal life; this gives NCCs potential for regeneration (Miletich, 2004). There are four types of neural crest cells: cranial (bone/cartilage), cardiac, vagal, and trunk; these show just how multipotential these cells really are, making them great for regenerative medicine (Zhao and Chai, …show more content…
Front. Physiol. 6:289. doi: 10.3389/fphys.2015.00289
Retrieved from: http://journal.frontiersin.org/article/10.3389/fphys.2015.00289/abstract
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