The Human Genome Project
PM 595 Project Risk Management
Course Project
The Human Genome Project
Submitted by
Rodney A. Lee
Instructor – Keith Bluestein
August 15, 2011
Table of Content
Introduction ……………………………………………………………………………….3
The Human Genome Project ……………………………………………………………..4
Decision Tree ……………………………………………………………………………..5
Decision Tree 1 ……………………………………………………………………...6
Risk Identification …………………………………………………………………...........6
Decision Tree 2 ……………………………………………………………………...10
Risk Management ………………………………………………………………………...14
Risks Assessment for Decision Trees 1& 2 ……………………………………………...15
Potential Risks for Participants in Genetic Testing ………………………………..17
Risk Mitigation ………………………………………………………………………..….18
Risk Acceptance Strategy ……………………………………………………………..….19
Risk Avoidance Strategy ………………………………………………………………....19
Risk Optimization Strategy ………………………………………………………………19
Risk Transference Strategy …………………………………………………………….…20
Conclusion ……………………………………………………………………….…….…21
Appendix ……………………………………………………………………………….…23
Reference …………………………………………………………………………………26
Introduction
Scientist over decades have explored and mapped lands, oceans and the heaven with the
expectation of increasing man’s awareness of the environment in which we live. The Human
Genome Project (HGP) served to explore our genetic environment to make us aware of the
beneficial resources that contribute to understanding and improving our lives. The HGP
involved the discovery of the full Deoxyribonucleic Acid (DNA) complement in a single human
somatic cell. The project purpose was to sequence this sequence of DNA so that a map of it may
be produced that shows the location and arrangement of all of the base pairs present in a human
being.
The HGP initial goals were to: * identify all the approximately 20,000-25,000 genes in human DNA * determine the sequences of the 3 billion
Course Project
The Human Genome Project
Submitted by
Rodney A. Lee
Instructor – Keith Bluestein
August 15, 2011
Table of Content
Introduction ……………………………………………………………………………….3
The Human Genome Project ……………………………………………………………..4
Decision Tree ……………………………………………………………………………..5
Decision Tree 1 ……………………………………………………………………...6
Risk Identification …………………………………………………………………...........6
Decision Tree 2 ……………………………………………………………………...10
Risk Management ………………………………………………………………………...14
Risks Assessment for Decision Trees 1& 2 ……………………………………………...15
Potential Risks for Participants in Genetic Testing ………………………………..17
Risk Mitigation ………………………………………………………………………..….18
Risk Acceptance Strategy ……………………………………………………………..….19
Risk Avoidance Strategy ………………………………………………………………....19
Risk Optimization Strategy ………………………………………………………………19
Risk Transference Strategy …………………………………………………………….…20
Conclusion ……………………………………………………………………….…….…21
Appendix ……………………………………………………………………………….…23
Reference …………………………………………………………………………………26
Introduction
Scientist over decades have explored and mapped lands, oceans and the heaven with the
expectation of increasing man’s awareness of the environment in which we live. The Human
Genome Project (HGP) served to explore our genetic environment to make us aware of the
beneficial resources that contribute to understanding and improving our lives. The HGP
involved the discovery of the full Deoxyribonucleic Acid (DNA) complement in a single human
somatic cell. The project purpose was to sequence this sequence of DNA so that a map of it may
be produced that shows the location and arrangement of all of the base pairs present in a human
being.
The HGP initial goals were to: * identify all the approximately 20,000-25,000 genes in human DNA * determine the sequences of the 3 billion
References: Perseus Books, 1998. Genomes.Engery.Gov (2008). Human Genome Project Information. Retrieved from http://www.ornl.gov/sci/techresources/Human_Genome/elsi/elsi.shtml Landers, E.S., Linton, L.M., Birren, B. et al (2001). Initial sequencing and analysis of the human genome Marshall, Elliot (1998 October). “New goals for the U.S. Human Genome Project: 1998-2003”. Science National Human Genome Research Institute. (2007d). Summary of genetic information non- discrimination act of 2003 (S.1053) Ringdahl, Chad, (1999). The Human Genome Project. Retrieved from http://www.ndsu.edu/pubweb/~mcclean/plsc431/students99/ringdahl.htm Schwartz, Ariel (2011). The Human Genome project 's $800 billion economic impact. Retrieved from http://www.msnbc.msn.com/id/43008755/ns/business-us_business/ U.S. Dept. of Energy (1999). Human Genome News. BAC End Sequencing Speeds Large and Small Projects Venter, J.C., Adams, M.D., Myers, E.W., et al (2001). The sequence of the human genome. Science 16; 291 (5507): 1304-51.