Schettler, T. (2001). Toxic threats to neurologic development of children. Environmental Health Perspective 109(6). P. 813–6 Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240616/pdf/ehp109s-000813.pdf…
Target Organ and Other Health Effects: • Blood disorders • Liver injury may occur. • Causes headache, drowsiness or other effects to the central nervous system. This product contains ingredients that may contribute to the following potential chronic health effects: • Notice: Reports have associated repeated and prolonged occupational overexposure to solvents with permanent brain and nervous system damage. Intentional misuse by deliberately concentrating and inhaling the contents may be harmful or fatal. • Prolonged exposure over TLV may produce pneumoconiosis. • Possible sensitization.…
1. The advantages of organic food, you are what you eat: An article about organic food and diseases in non-organic food…
Are your chemicals Endocrine disruptors, carcinogens or teratogens? (also known as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds) This might require some additional research. Please cite your references. Health effects labeled on the household products database state no chronic health effects reported. Plus under Carcinogencity for NTP and IARC was claim none was reported. (Consumer Product Information Database, 2001-2013)…
Following metabolism the metabolites are excreted in the urine and faeces. No data on the acute effects of B(a)P in humans were identified and few studies were reported in animals. Following acute exposure of rats to B(a)P, effects on the liver were observed. Following chronic exposure in an occupational setting a decrease in lung function was reported, as well as chest pain, respiratory irritation, cough, dermatitis and depressed immune system, although in most cases it was not possible to evaluate the contribution of B(a)P to such effects. In animals, few adverse effects were observed in rats or hamsters exposed to B(a)P via inhalation. Following ingestion, myelotoxicity was observed in poor affinity Ah-receptor mice but not in high affinity mice. Hepatotoxicity was also reported. Benzo(a)pyrene can cross the placenta and was found to cause adverse developmental and reproductive effects in…
TriCyclic Antidepressants (TCAs). This kind of antidepressants are one of the first drugs to be used for treating depression. TCAs work the same way as SNRIs. However, TCAs affect other chemical messengers, which cause many side effects. TCAs have been replaced in popularity due to the side effects they bring, which include urinary retention, constipation, weight loss, weight gain due to increased appetite, profuse sweating, tremors, delayed orgasms, lowered sex drive, tremors, blurred vision, dizziness and drop in blood pressure. Some doctors still prescribe TCAs when other kinds of medication have failed. The most used TCAs include amitriptyline, amoxapine, desipramine (Norpramin), doxepin, imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil) and trimipramine (Surmontil).…
o Exposure to many different chemicals o Latency period (timing of exposure) o Lack of data (why?) o Human testing almost impossible Case study: Endocrine disruptors • Endocrine disruption: certain chemicals linked with known carcinogens that alter or disturb hormones or endocrine system • Endocrine disruptors “trick (“xeno” or false endocrines) body into believing they are supposed to play a role in bodies functions” -‐ “sabotage normal bodily functions” (Krimsky 2001) • Disruptors mimic or obstruct role of natural hormones • No single mechanism or pattern to interference or disruption • Impacts on humans: o Sperm count declines, cancer incidence (breast, testicular and prostate), neurological disorders o Estrogens known to activate growth of certain classes of cancer cells o Linked to organochlorines that function as xeno-‐endocrines § Bisphenol (BPA) • Endocrine disruptors challenge conventional notion that “the dose makes the poison” o Linear or monolithic dose-‐response curve?…
~Aspirin is used to treat pain due to inflammation. It also used to treat several conditions such as…
The teratogen I choose to do this assignment on is Cytomegalovirus (CMV). The reason why I choose this teratogen is because I wanted to learn more about it and how to prevent this infectious disease. I am aware it is closely related to Herpes. I want to know what similarities and difference Cytomegalovirus had compared with Herpes.…
During anesthesia, there is a great amount of drugs used to suppress the pain that would occur to the body. There are some common drugs that are used. Alcohol, Aspirin, Lidocaine, Morphine, and Succinylcholine are all used during anesthesia. Each is used to interrupt the pain signals during surgeries. Without these medications, the body would not be able to withstand such trauma occurring to perform the procedure fully.…
Noel Stanton WI State Lab of Hygiene 2601 Agriculture Drive PO Box 7996 Madison WI 53707 (608) 224-6251 nvstox@mail.slh.wisc.edu – Homeostasis • Abundance = toxicity • Every truism has exceptions Speciation Considerations • Can greatly influence toxicity • Ability to differentiate limited, improving – Cr+3 = nutrient, Cr +6 = carcinogen – Toxicity As+3 > As+5 >>organic As or Exposure Routes ? Assessment • Contamination biggest concern – serum Al: 1970 = 1,000 µg/L, 2002 = 2 µg/L • Ingestion—most common • Inhalation—more dangerous Mechanisms of Action • Binding to SH groups – alters protein shape • Substitution for nutritional element • Best sample will be element and species dependent – correlation w/disease often limited – Blood, urine, serum typical – Hair is generally NOT valid • Analytical methods – Atomic spectrometry (AA, ICP-MS)…
Hazard identification is an important part of learning about pesticides and whether or not to use them. This asks the question; Does exposure to substance caused increased likelihood of adverse health effects such as cancer or birth defects. When planning to use chemicals like Malathion it is important to learn as much as possible about it. Malathion is a man-made organophosphate insecticide that is commonly used to control mosquitos and a variety of insects that attack fruits vegetables, landscaping plants, and shrubs. (Department of Health, 2009). Malathion is also used indoors to control insects and ticks on pets like cats and dogs. Short-term exposure to high levels of Malathion affects the nervous system causing increased heart rate, nausea, headaches, diarrhea, and cramps. I have found no information on long-term effects on humans due to exposure. This doesn’t mean that is none, it means…
Unit 7. Assignment 2. The Effects of Selected Drugs and Diseases on the Central Nervous System.…
The increase in desire for perfect produce, drives the need for pesticides today. Much debate of the effects of chemicals used on commercial crops and overall long term effects on humans is an increasing concern. With the increase in advertising of organic produce, many standards of farming have been criticized. Many are claiming a large increase in risk to humans for consuming commercially grown produce, because of the chemicals used to manage such a large volume of crops. There have been many debates of the actual risk of pesticide consumption. With advancing technology and farm equipment, many types of chemical sprays and powders have been used. The actual effect of these pesticides and long term exposure can be harmful to human health.…
The Medicines Act 1968 is an Act of Parliament of the United Kingdom. It governs the control of medicines for human use and for veterinary use, which includes the manufacture and supply of medicines. The Act defines three categories of medicine: prescription only medicines), which are available only from a pharmacist if prescribed by an appropriate practitioner; pharmacy medicines, available only from a pharmacist but without a prescription; and general sales list medicines which may be bought from any shop without a prescription.…