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Saffron not only used in a cooking purposes but it is miraculously used in medicinal properties since long time ago. According to Xuan (1999), saffron has a benefits effect on ocular blood flow and retinal function. Saffron used to prepare a special eye formulation which is called as collyrium. The function of collyrium is to treat a range of ophthalmic disorders such as cataract and conjunctivitis that help to improve the human vision. The carotenoid crocin has protective effect against blue light and white light induced rod and cone death in the dim and primate retinal cell cultures. Saffron extract along with crocetin and crocin increased the blood flow in the retina, induced retinal damage and also as a treatment of asthma. While choroid used to treat ischemic retinopathy and also prevention of age-related macular degeneration. According to Professor Silvia Bisti who carried out the research on patients with age-related macular degeneration, he shows that the patient’s vision was improved after taking the saffron pill.
Besides that, saffron also has the effect on coronary artery disease. As we know, saffron has an antioxidants that can help to reduce the risk of coronary artery disease. The flavonoids such as lycopene that found in saffron has potential to provide added protection from coronary artery disease. Verma and Bordia (1998), stated that fifty milligrams of saffron that dissolve into 100 milliliter of milk twice a day will decrease in lipoprotein oxidation in patients with coronary artery disease. In addition, saffron has been found to be the richest source of riboflavin. Riboflavin is also known as vitamin B2 and easily absorbed colored micronutrient. It is important for body growth and red blood cell production. The presence of crocetin in saffron, indirectly help to reduce the cholesterol in the blood and reduce the chances of heart attacks. In Spain, saffron is consumed freely because of rate of coronary artery disease is fairly low. Hence, the