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Summary: Hepatoprotective Nature Of Murraya Koenigii

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Summary: Hepatoprotective Nature Of Murraya Koenigii
ETHNOMEDICAL SURVEY

This survey was conducted in a Malay village name kampong Tanjung Sabtu located at West Kuala Terengganu, the capital city of Terengganu in Peninsular Malaysia. Most the villagers are farmers and some government staffs. This data obtain from the conversation adult villager, local healer and herbalist by using the ethnomedical enquiries. Mostly the villagers willing to share their knowledge on the uses of some medicinal plants. Total 52 plants were recorded to be used among the villagers. Among that plants we get to know that Murraya koenigii commonly known as curry leaves taken orally in decoction of roots to treat dysentery and also the leaves used mainly in all the curry. This survey also give us the information that
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koenigii leaves extract. The effect was due to the combined effect of carbazole alkaloids such as Girinimbine, Mahanine, Mahanimbine, Isomahanimbine, Murrayazolidine, Murrayazoline and minerals such as Zinc, Iron, Copper along with α-tocopherol and ascorbic acid, extracted from the leaves. Thus M. koenigii is a favorable and a rich source of free radical quencher. The process is mediated through hepatocyte membrane stabilizing activity along with the reduction of fat metabolism.

Capability of enhancing memory Total alkaloid extracts of Murrya koenigii leaves, in doses of 20 and 40 mg/kg p.o., improves the values of protective antioxidants like catalase, glutathione peroxidase, glutathione reductase, reduced glutathione and superoxide dismutase in brain homogenates. An increase in the acetylcholine levels and decrease in anticholinesterase activity has also been noticed. Thus, these properties play a beneficial role in protection against neurodegenerative diseases such as Alzheimer’s. The leaf extracts also show a significant improvement in cognitive functions in aged mice, such as improvement in memory that could be used in the management of

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