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Risk Factors For Alzheimer's Disease

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Risk Factors For Alzheimer's Disease
Alzheimer’s disease is a neurodegenerative disorder characterized clinically by progressive cognitive impairment [1]. Age is the most important factor that predisposes persons to the non-familial form of the disease, which in 2010 affected over 35 million elderly adults worldwide [2]. How aging interacts with other risk factors for Alzheimer’s disease [3] is still unknown. It appears, however, that certain age-related pathologies that are closely associated with systemic dysfunctions in lipid metabolism –including obesity and diabetes –might be involved [1]. The polyunsaturated lipid, docosahexaenoic acid (C22:6n-3), is an essential component of neuronal membranes [4,5] and a precursor for potent neuroprotective mediators [6–8]. Mammals obtain
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