Prostate Cancer Synthesis Essay

The development of prostate cancer within the contemporary society is seen as the most common form of virulent disease state affecting the male population especially within America (Yu et al. 2790). The progression of the cancer to an aggressive form is yet to be determined especially regarding what specific molecular mechanisms cause the cancer to turn severe (Yu et al. 2790). Prostate cancer grows through different stages such as the perinvasive period, the invasive stage and lastly androgen-independent or dependent stage leading to metastasis (Welsh et al. 5974) throughout the body. Furthermore, to fully understand the how and why behind prostate cancer is to efficiently study the gene expression and the biomarkers that are present at the time of the development of the cancer.
Various studies have been conducted regarding the
1). MicroRNA’s have the potential to communicate within the metabolic pathways causing them to altercate their regulation and expression causing normal functioning to be affected (Jackson et al. 1). The small RNA units demonstrate involvement in oncogenic reactions as the microRNA’s have shown characteristics that are seen within the growth of cancers such as cell death, metastasis, and cell growth (Jackson et al. 2). Furthermore, studies have been conducted by researchers on how microRNA’s are serving as biomarkers for prostate cancer. For example, multiple different microRNA units were chosen to understand their circulation and if certain small nucleotides showed overexpression if their levels were increased within the presence of cancer (Jackson et al. 5). Based on the study, certain microRNA’s showed high signs of elevation and overexpression in connection with cancer (Jackson et al. 5) leading to further understanding of how microRNA’s can serve to be biomarkers when needed for diagnostic