Propofol Alternatives In Gastrointestinal Endoscopy
ISSN 1658-354X
Saudi Journal of Anesthesia • Volume 8 • Issue 4 • October-December 2014 • Pages 447-574
Saudi
Journal of
Anesthesia
Official Publication of The Saudi Anesthesia Association
October-December 2014 / Vol 8 / Issue 4
www.saudija.org
REVIEW ARTICLE
Page | 540
Propofol alternatives in gastrointestinal endoscopy anesthesia Basavana Gouda Goudra,
Preet Mohinder Singh1
A B S T R A C T
Department of Clinical
Anesthesiology and Critical Care,
Perelman School of Medicine,
680 Dulles Building, 3400 Spruce
Street, Philadelphia, PA 19104,
USA, 1Department of Anesthesia, All
India Institute of Medical Sciences,
New Delhi, India
Address for correspondence:
Dr. Basavana Goudra, Department of
Clinical Anesthesiology and Critical
Care, Perelman School of Medicine,
680 Dulles Building, 3400 Spruce
Street, Philadelphia, PA 19104, USA.
E-mail: goudrab@uphs.upenn.edu
Although propofol has been the backbone for sedation in gastrointestinal endoscopy, both anesthesiologists and endoscopists are faced with situations where an alternative is needed. Recent national shortages forced many physicians to explore these options.
A midazolam and fentanyl combination is the mainstay in this area. However, there are other options. The aim of this review is to explore these options. The future would be, invariably, to move away from propofol. The reason is not in any way related to the drawbacks of propofol as a sedative. The mandate that requires an anesthesia provider to administer propofol has been a setback in many countries. New sedative drugs like
Remimazolam might fill this void in the future. In the meantime, it is important to keep an open eye to the existing alternatives.
Key words: GI endoscopy sedation, non-anesthetist administered propofol, propofol complications in sedation, propofol Remimazolam
INTRODUCTION
During the recent national shortages of propofol, physicians started to look for alternatives with similar properties. A major setback to the use of
Saudi Journal of Anesthesia • Volume 8 • Issue 4 • October-December 2014 • Pages 447-574
Saudi
Journal of
Anesthesia
Official Publication of The Saudi Anesthesia Association
October-December 2014 / Vol 8 / Issue 4
www.saudija.org
REVIEW ARTICLE
Page | 540
Propofol alternatives in gastrointestinal endoscopy anesthesia Basavana Gouda Goudra,
Preet Mohinder Singh1
A B S T R A C T
Department of Clinical
Anesthesiology and Critical Care,
Perelman School of Medicine,
680 Dulles Building, 3400 Spruce
Street, Philadelphia, PA 19104,
USA, 1Department of Anesthesia, All
India Institute of Medical Sciences,
New Delhi, India
Address for correspondence:
Dr. Basavana Goudra, Department of
Clinical Anesthesiology and Critical
Care, Perelman School of Medicine,
680 Dulles Building, 3400 Spruce
Street, Philadelphia, PA 19104, USA.
E-mail: goudrab@uphs.upenn.edu
Although propofol has been the backbone for sedation in gastrointestinal endoscopy, both anesthesiologists and endoscopists are faced with situations where an alternative is needed. Recent national shortages forced many physicians to explore these options.
A midazolam and fentanyl combination is the mainstay in this area. However, there are other options. The aim of this review is to explore these options. The future would be, invariably, to move away from propofol. The reason is not in any way related to the drawbacks of propofol as a sedative. The mandate that requires an anesthesia provider to administer propofol has been a setback in many countries. New sedative drugs like
Remimazolam might fill this void in the future. In the meantime, it is important to keep an open eye to the existing alternatives.
Key words: GI endoscopy sedation, non-anesthetist administered propofol, propofol complications in sedation, propofol Remimazolam
INTRODUCTION
During the recent national shortages of propofol, physicians started to look for alternatives with similar properties. A major setback to the use of