Physioex 8.0 Exercise 10
Respiratory Acidosis and Alkalosis
Activity 1: Normal Breathing
1. At 20 seconds, pH = 7.4 2. At 40 seconds, pH = 7.4 3. At 60 seconds, pH = 7.4 4. Did the pH level of the blood change at all during normal breathing? If so, how? No, it stayed at 7.4 5. Was the pH level always within the “normal” range for the human body? Yes 6. Did the PCO2 level change during the course of normal breathing? If so, how? No, it stayed at 40mm Hg
Activity 2a: Hyperventilation – Run 1
1. At 20 seconds, pH = 7.43 2. At 40 seconds, pH = 7.52 3. At 60 seconds, pH = 7.67 4. Maximum pH = 7.68 5. Did the pH level of the blood change at all during this run? If so, how? Yes pH levels in the blood did change, they increased over the course of the run 6. Was the pH level always within the “normal” range for the human body? If not, when was the pH value outside of the normal range, and what acid/base imbalance did this pH value indicate? No the pH levels were not in the “normal” range for the human body. Beginning at 40 seconds, with the pH at 7.52, respiratory alkalosis occurred. 7. Did the PCO2 level change during the course of this run? If so, how? Yes the PCO2 levels did fluctuate over the course of this run decreased from 40mm Hg to 19.7mm Hg 8. If you observed an acid/base imbalance during this run, how would you expect to renal system to compensate for this condition? Renal compensation for alkalosis means the kidneys will correct the basic conditions by increasing H+ absorption and by increasing bicarbonate (HCO3-) secretion. 9. How did the hyperventilation trace differ from the trace for the normal breathing? Did the tidal volumes change? The amount of air inspired and expired (tidal volume) increased from the normal value of around 500ml to around 3 Liters 10. What might cause a person to hyperventilate? Anxiety, stress, or panic attacks, caused by over breathing
Activity 2b: Hyperventilation – Run 2
Activity 1: Normal Breathing
1. At 20 seconds, pH = 7.4 2. At 40 seconds, pH = 7.4 3. At 60 seconds, pH = 7.4 4. Did the pH level of the blood change at all during normal breathing? If so, how? No, it stayed at 7.4 5. Was the pH level always within the “normal” range for the human body? Yes 6. Did the PCO2 level change during the course of normal breathing? If so, how? No, it stayed at 40mm Hg
Activity 2a: Hyperventilation – Run 1
1. At 20 seconds, pH = 7.43 2. At 40 seconds, pH = 7.52 3. At 60 seconds, pH = 7.67 4. Maximum pH = 7.68 5. Did the pH level of the blood change at all during this run? If so, how? Yes pH levels in the blood did change, they increased over the course of the run 6. Was the pH level always within the “normal” range for the human body? If not, when was the pH value outside of the normal range, and what acid/base imbalance did this pH value indicate? No the pH levels were not in the “normal” range for the human body. Beginning at 40 seconds, with the pH at 7.52, respiratory alkalosis occurred. 7. Did the PCO2 level change during the course of this run? If so, how? Yes the PCO2 levels did fluctuate over the course of this run decreased from 40mm Hg to 19.7mm Hg 8. If you observed an acid/base imbalance during this run, how would you expect to renal system to compensate for this condition? Renal compensation for alkalosis means the kidneys will correct the basic conditions by increasing H+ absorption and by increasing bicarbonate (HCO3-) secretion. 9. How did the hyperventilation trace differ from the trace for the normal breathing? Did the tidal volumes change? The amount of air inspired and expired (tidal volume) increased from the normal value of around 500ml to around 3 Liters 10. What might cause a person to hyperventilate? Anxiety, stress, or panic attacks, caused by over breathing
Activity 2b: Hyperventilation – Run 2