Name: _________________________________ EXERCISE 3
Neurophysiology of Nerve Impulses Laboratory Report
Answer the following questions. (3 points each).
1. What is the difference between membrane irritability and membrane conductivity? Membrane irritability is the ability to respond to a stimuli and convert it in to nerve impulses. Membrane conductivity is the ability to transmit that impulse that is created by membrane irritability.
2. If you were to spend a lot of time studying nerve physiology in the laboratory, what type of stimulus would you use, and why? You would use a electric stimulus, this is because with the electric stimulus you can adjust and determine the pressure, frequency, duration, and voltage and control them. 3. Briefly explain how the addition of NaCl in the ECF elicit an action potential? With the addition of more Na ions it increases the concentration of Na ions outside the cell. The driving force of the action potential is the increase in the concentration gradient because of the increase of Na ions outside the cell. 4. General anesthetics such as ether and chloroform open K+ gated-channels in the brain. What would be the effect of inhaled ether on the generation of action potentials in neurons in the brain of a rat exposed to this anesthetic? Provide a good and brief physiological explanation.
In activity 7 you tested the effect of lidocaine on eliciting an action potential. Answer the following: 5. What is lidocaine (type of macromolecule)
Lidocaine (2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide) is a topical anesthetic used for dental surgeries or other minor surgeries. 6. List three (3) common use of lidocaine.
Relieves itching and burning due to skin inflammation. 7. Lidocaine blocks fast voltage gated sodium (Na+) channels in the cell membrane of nerve fibers. How...
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