Physchology essay Fatal Familial Insomnia

Topics: Prion, Bovine spongiform encephalopathy, Transmissible spongiform encephalopathy Pages: 2 (572 words) Published: April 23, 2014

Presentation Summary

Fatal Familial insomnia (FFI)

What is Fatal Familial Insomnia? Also known as FFI. Fatal Familial Insomnia (FFI) is a genetic sleep disorder - but it is a rare one. It has been diagnosed in less than 40 families worldwide, including the Chicago music teacher, Michael Corke, who featured in the BBC documentary The Man Who Never Slept. FFI begins as an unexplained sleeplessness during middle age and rapidly develops into a fatal insomnia. It is caused by a genetic mutation which leads to a prion disease, related in nature to Mad Cow Disease (BSE or CJD) and Kuru (the laughing disease found in cannibalistic tribes in New Guinea) and even Alzheimer's Disease. Prions are the missing link between all these diseases, and they tell us a lot about the nature of protein molecules and their ability to cause death.

Fatal insomnia is a baffling condition (and only officially discovered 10 years ago) because its symptoms resemble many common diseases - like dementia, end-stage alcoholism and encephalitis. The main symptom of FFI is the inability to sleep, and this causes high pulse and blood pressure, excessive sweating and a loss of coordination and motor skills. The disease manifests itself in four deteriorating stages: STAGE ONE - The sudden and inexplicable onset of insomnia causes panic attacks and unfounded phobias, lasting for about four months. (Longest FFI case lasted 18 Months before the victim died of being deprived from sleep) STAGE TWO - As sleep deprivation takes hold, the panic attacks and hallucinations become severe, lasting for a further five months. STAGE THREE - The total insomnia causes rapid weight loss and limited mental functioning, lasting for up to three months. STAGE FOUR - Finally, the patient suffers from dementia and unresponsiveness, lasting for up to six months. Eventually the patient falls into a coma and dies from total insomnia. One of the most tragic aspects of FFI is that though the sufferer shows signs...
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