Phobianation
Dela Cruz, Catherine V. Genetics and Evolution Prof. Genelita Garcia
Obio, Mary Joy A. Written Report
Stem Cell Technology
Stem Cells – cells that have the ability to continuously divide and differentiate into various other kind of cells.
Characteristics:
* Simple, remain the same cell in constant environment * Continuous mitotic divisions * With proper stimuli/environment it can differentiate into various cells
Classification:
Type of cells | Description | Source | Totipotent | Can give rise to a whole organism | Fertilized egg cell | Pluripotent | Can give rise to any cell but not an entire organism | Embryonic stem cells | Multipotent | Can give rise to cells within the same lineage | Adult stem cells | * According to potency * According to sources
Embryonic – stem cells that can be collected in the inner mass of the blastula.
Adult - Stem cells reside in a microenvironment known as the niche. Schofield, who was the first to put forth the concept of stem cell niche, proposed that the niche: (1) provides an anatomic space to regulate stem cell number, (2) instructs a stem cell to either self-renew in close proximity or commit to differentiation at a distance, and (3) influences stem cell motility. Adult | Location (niche) | Stem cells | Growth factor | Give rise to | Bone | Bone marrow-soft, spongy tissue found inside bones. It is the medium for development and storage of most of the body's blood cells. | Hematopoetic cells | (G-CSF) granulocyte- colony stimulating factor | Blood cells | Blood | | Hematopoetic cells | (G-CSF) granulocyte- colony stimulating factor | Blood cells | Teeth | Pulp of teeth | | | | Brain | Hippocampus-located within the temporal lobes, adjacent to the amygdala.- involved in memory forming, organizing, and storing. | Neural stem cells | NGF [Nerve Growth Factor] | NeuronsAstrocytesOligodendrytes | Skin | Basal layer of epidermis?Basal layer of hair follicle | Follicular
Obio, Mary Joy A. Written Report
Stem Cell Technology
Stem Cells – cells that have the ability to continuously divide and differentiate into various other kind of cells.
Characteristics:
* Simple, remain the same cell in constant environment * Continuous mitotic divisions * With proper stimuli/environment it can differentiate into various cells
Classification:
Type of cells | Description | Source | Totipotent | Can give rise to a whole organism | Fertilized egg cell | Pluripotent | Can give rise to any cell but not an entire organism | Embryonic stem cells | Multipotent | Can give rise to cells within the same lineage | Adult stem cells | * According to potency * According to sources
Embryonic – stem cells that can be collected in the inner mass of the blastula.
Adult - Stem cells reside in a microenvironment known as the niche. Schofield, who was the first to put forth the concept of stem cell niche, proposed that the niche: (1) provides an anatomic space to regulate stem cell number, (2) instructs a stem cell to either self-renew in close proximity or commit to differentiation at a distance, and (3) influences stem cell motility. Adult | Location (niche) | Stem cells | Growth factor | Give rise to | Bone | Bone marrow-soft, spongy tissue found inside bones. It is the medium for development and storage of most of the body's blood cells. | Hematopoetic cells | (G-CSF) granulocyte- colony stimulating factor | Blood cells | Blood | | Hematopoetic cells | (G-CSF) granulocyte- colony stimulating factor | Blood cells | Teeth | Pulp of teeth | | | | Brain | Hippocampus-located within the temporal lobes, adjacent to the amygdala.- involved in memory forming, organizing, and storing. | Neural stem cells | NGF [Nerve Growth Factor] | NeuronsAstrocytesOligodendrytes | Skin | Basal layer of epidermis?Basal layer of hair follicle | Follicular