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Pathological Pain Lab Report

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Pathological Pain Lab Report
INTRODUCTION

Pain is an important sensation that alerts to a threatening condition in the body’s tissues.1 Like hunger or thirst, it is a motivational somatic state that drives appropriate behavioral responses, but chronic pathological pain can also completely dominate attention and consciousness and cause intolerable suffering.2 Our knowledge of the representation of pain in the peripheral nerves, the spinal cord, and the brain is increasing, and become aware that many neurochemicals involved and the critical interactions with other systems, such as the thermoregulatory, sympathetic and immune systems, that make pain an integrated physiological phenomenon.3-5

The clinical treatment of pain has improved with the advent of local and spinal
…show more content…
Group 1 (-ve control group), they were given normal saline. 2. Group 2 (+ve control group) (acetylsalicylic acid), they were treated with acetylsalicylic acid in a dose of 50 mg/kg and was given (i.p) one hour prior to the experiment. 3. Group 3 (Passiflora group), they were treated with Passiflora in a dose of (1 drop per 1 ml d.w.) and was given (orally) one hour prior to the experiment. 4. Group 4 (Cinnamon group), they were treated with Cinnamon in a dose of (0.3 ml) and was given (orally) one hour prior to the experiment. 5. Group 5 (Chamomile group), they were treated with Chamomile in a dose of (0.3 ml) and was given (orally) one hour prior to the experiment.

Extraction

Chamomile and cinnamon
Dried powder of the plant material (coarse powder) placed into a distilling flask and add few pieces of porous earthenware. Add 200ml D.W to the flask and shake well. Add another 200ml of water by rinsing the neck of the flask. Connect the distilling flask with the still head of the apparatus. By the means until over flowsConnect the condenser of the apparatus with the cooling water (from the tap).Heat the distilling flask until the boiling starts. Record the time of the beginning of distillation, and continue the distillation for one hourSwitch off the heating. Allow the graduated receiver to cool. 16

Passiflora
The air-dried, powdered plant material was extracted with petroleum ether and Ethanol using soxhlet apparatus.

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