Oxidative Stress And Alzheimer's Disease
Oxidative Stress
Oxidative Stress occurs when the generation of free radical Oxidative stress has been implicated in several diseases Including ca ncer, atherosclerosis, malaria, chronic fatigue syndrome, rheumatoid arthritis and neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease (Figure ) Oxidative stress results from an imbalance between production of reactive oxygen and nitrogen species (ROS and RNS, respectively) and endogenous antioxidant defense mechanisms. Increased generation of ROS/RNS is implicated in the pathogenesis of a variety of human diseases, including neurodegenerative disease, atherosclerosis, cancer and aging. (Lee and Blair, 2001; Dotan et al., 2004 and Milatovic
Oxidative Stress occurs when the generation of free radical Oxidative stress has been implicated in several diseases Including ca ncer, atherosclerosis, malaria, chronic fatigue syndrome, rheumatoid arthritis and neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease (Figure ) Oxidative stress results from an imbalance between production of reactive oxygen and nitrogen species (ROS and RNS, respectively) and endogenous antioxidant defense mechanisms. Increased generation of ROS/RNS is implicated in the pathogenesis of a variety of human diseases, including neurodegenerative disease, atherosclerosis, cancer and aging. (Lee and Blair, 2001; Dotan et al., 2004 and Milatovic