Onion and Calamansi Extract to Kill Coackroaches

°Thioridazine hydrochloride,USP. Is a member of the piperizine subgroup of the phenothiazines. Thioridazine occurs as a white or slightly yellow, crystalline or micronized powder, which is odourless or has a faint odor and is practically insoluble in water and freely soluble in dehydrated alcohol. The drug has sedative and hypotensive activity in common with chlorpromazine and less antiemetic activity. thioridazine is indicated for the treatment of schizophrenic patients who fail to respond adequately to treatment with other antipsychotic drugs. ® perphenazine, USP. Is indicated for use in the management of the manisfestations of psychotic disorders and for the control of severe nausea and vomiting in adults. ® trifluoperazine hydrochloride The absorption of trifluoperazine is erratic and variable and it is widely distributed into tissues. The metabolism and drug interactions of trifluoperazine are the same as with the other phenothiazines. It does not show any specific drug interactions. It is indicated for the management of schizophrenia and short-term treatment of nonpsychotic anxiety. ® Thiothixene, USP. The absorption of thiothixene is erratic because of its high lipophilicity. It is widely distributed inti tissues and it is more than 90% bound to plasma proteins. Thiothixene has a similar metabolic pathway sa the phenothiazines. As with other antipsychotic agents, some patients who are resistant to previous medication s have responded favourably to thiothixene. It may also be of value in the management of withdrawn, apathetic schizophrenic patients. • BUTYROPHENONES AND RELATED STRUCTURES Haloperidol was discovered by Jensen Laboratories (1958) as a byproduct while they were investigating analgesics structurally related to meperidine. The behavioural profile of haloperidol was found to be very similar with that of chlorprpmazine, but the required was about 50-fold less to exert the same bahavioral effect. It was rapidly