Preview

Nutmeg and Natural Source

Satisfactory Essays
Open Document
Open Document
467 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Nutmeg and Natural Source
Nutmeg
Isolation of Trimyristin from Nutmeg and preparation of Myristic Acid from Trimyristin by Hydrolysis
Introduction
Over 40% of medicinal chemicals in the world were developed from isolation of the natural source. These sources were from fungi, plants, bacteria, animals, etc. The techniques used to isolate and purify has been by extraction, distillation, recrystallization, and chromatography. In this experiment we will be trying to obtain a pure organic compound from a natural source. Because this natural source it is not only trimyristin and myristic acid that makes it up, it’s a mixture of many compounds. Although nutmeg is one of those natural sources that trimyristin is easily extracted from it does take some time to achieve in lab. Ground nutmeg seeds are extracted with methyl ether and the resulting solid recrystallized from acetone and to yield pure trimyristin. Most of the other components of Nutmeg remain in the acetone as they are ether soluble. The hydrolysis of trimyristin follows acidification and yields glycerol and myristic acid. After the myristic acid is collected we will be using its melting point to determine whether we successfully isolated pure form of the crystal. To extract myristic acid from our “pure” trimyristin we need perform hydrolysis and break a couple of those bonds to get it.
Hydrolysis
Trimyristin
Myristic Acid
Glycerol
Side reaction of myristic acid
Experimental Section
Table of Chemicals
Name | Chem Structure | Atomic weight | Melting point |
Isolation of Trimyristin from Nutmeg and preparation of Myristic Acid from Trimyristin by Hydrolysis
Introduction
Over 40% of medicinal chemicals in the world were developed from isolation of the natural source. These sources were from fungi, plants, bacteria, animals, etc. The techniques used to isolate and purify has been by extraction, distillation, recrystallization, and chromatography. In this experiment we will be trying to obtain a pure organic compound from a

You May Also Find These Documents Helpful

  • Good Essays

    The Aldehyde Enigma

    • 817 Words
    • 4 Pages

    This experiment was performed in collaboration with Paula Mendoza. Exceptions to the procedure are: no NMR or wet chemical test for both compounds. Since there was a lack of organic compound we were unable to proceed with any of the identifying tests.…

    • 817 Words
    • 4 Pages
    Good Essays
  • Good Essays

    In this experiment we also used a chemical method known as extraction. This process of separation is used when only one component of the mixture is soluble in a specific solvent. In our case we had to use hydrochloric acid (HCl).Extractions, is a way to separate a desired substance when it is mixed with others. The mixture is brought into contact with a solvent in which the substance of interest is soluble, but the other substances present are insoluble. And below is a…

    • 854 Words
    • 4 Pages
    Good Essays
  • Good Essays

    The purpose of this experiment was to use solvent extraction techniques in order to separate a mixture consisting of a carboxylic acid (p-toulic acid), a phenol (p-tert-butylphenol), and a neutral compound (acetanilide). Extraction is the process of selectively dissolving one or more of the compounds of a mixture into an appropriate solvent, the solution that contains these dissolved compounds is called an extract (Manion, 2004).…

    • 1456 Words
    • 6 Pages
    Good Essays
  • Powerful Essays

    The product was then purified by flash chromatography and analyzed by IR, 1H NMR and 13C NMR.…

    • 1302 Words
    • 6 Pages
    Powerful Essays
  • Better Essays

    Chem Lab

    • 858 Words
    • 4 Pages

    There are millions of different organic compounds. Most of them are found in mixtures and in order to achieve a pure form they need to be separated, isolated, and purified. However, there are endless numbers of possible mixtures, which make it impossible to have a pre-designed procedure for every mixture. So chemists often have to make their own procedures. The purpose of this experiment was to prepare the student to the real world by them designing their own procedure which will help them understand the techniques of separation and purification better. The goal was to extract two of the components of the mixture that consisted of 50% benzoic acid, 40% benzoin, and 10% dibromobenzene. The benzoic acid was extracted by the use of base and extraction technique. Then a crystallization was performed in order to separate benzoin by the use of hexane a solvent, leaving the dibromobenzne in the mother liquor. The percent recovery for benzoic acid was 91.8% and 80.3% for the benzoin. The MP for benzoic acid was 119-122°C (1) and 135-136°C (2)for the benzoin. The high percent recovery and closeness of measured MP to the literature value indicate that the designed procedure was successful.…

    • 858 Words
    • 4 Pages
    Better Essays
  • Good Essays

    Experiment 55 consists of devising a separation and purification scheme for a three component mixture. The overall objective is to isolate in pure form two of the three compounds. This was done using extraction, solubility, crystallization and vacuum filtration. The experiment was carried out two times, both of which were successful.…

    • 1426 Words
    • 6 Pages
    Good Essays
  • Satisfactory Essays

    Medicines are attained from plants. Although its supply is limited due to weather changes, seasons and other aspects such as contamination hence, chemists were producing ways to the synthesis of this active ingredient by…

    • 439 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    Nutmeg European Influence

    • 582 Words
    • 3 Pages

    Commodities and spices of Indonesia attracted many European countries to step into the commodities trade and harvest in Indonesia. Through this involvement, the impact still remains apparent and unchangeable. Back then, nutmeg was the most desired luxury good in European in 16th and the 17th centuries. Nutmeg was literally more valuable than gold and this motivated the Europeans to search sea route to Asia, more specifically, the Spice Islands (“A Bloody Splice of Nutmeg’s History”). European influence on the Indonesian society actually started out as a positive impact. When the Portuguese arrived in the Spice Islands as the first Europeans to come to Ternate, they introduced new methods for harvesting cloves. Portuguese made the Malukans separate the cloves from branches and leaves, dry…

    • 582 Words
    • 3 Pages
    Good Essays
  • Good Essays

    The mixture (sample number: 27) was dissolved in 200 mL of CH2Cl2 and then extracted with 10% NaOH. The acid was removed by adding 3 x 50 mL of 10% NaOH. The neutral component in CH2Cl2 solution was set aside. The NaOH extracts were combined and then washed with 15 mL of CH2Cl2. The aqueous solution was acidified with 10% HCl. The solid yield (neutral component) was collected by vacuum filtration whereas the liquid yield (acidic component) was extracted into CH2Cl2 (3x25 mL). The acidic compound was then washed with 100 mL of water, dried over MgSO4, filtered. The solvent CH2Cl2 then was removed by evaporating it.…

    • 850 Words
    • 4 Pages
    Good Essays
  • Satisfactory Essays

    In this lab we separated components of a simulated preparation, panacetin and making use of its acid base properties. To obtain such a pure compound, the compound we want must be separated from its other natural components, which can be done by manipulating physical and chemical properties. Panacetin contains sucrose, aspirin and an unknown which can be acetanilide or phenacetin in which phenacetin was created and weighed.…

    • 479 Words
    • 2 Pages
    Satisfactory Essays
  • Powerful Essays

    Pavia, D. L. (2005). _Introduction to organic laboratory techniques: A small scale approach._ (pp. 451-452). Belmont, CA: Thomson Brooks/Cole.Top of Form…

    • 1307 Words
    • 11 Pages
    Powerful Essays
  • Good Essays

    Many techniques and skills were developed in this lab. Among them were dehydration, isolation, drying, and distillation. We used all of these techniques to get the product we were looking for. In addition to these experimental techniques we also verified our product via spectroscopy which is a new technique. Using IR spectroscopy we were able to specifically analyze the functional groups on our product.…

    • 1098 Words
    • 5 Pages
    Good Essays
  • Good Essays

    The preliminary steps in the isolation of the organic acid and organic base required volumes of approximately 10 mL and 8mL respectively of the inorganic acid or base (HCl or NaOH) in order to initiate the cloudy appearance in solution. Vacuum filtration of the NaOH extract (organic acid) produced a shiny white crystalline product collected in the filter paper. Likewise, vacuum filtration of the HCl extract (organic base) produced a dull white crystalline product collected in the filter paper, which was comparable to powdered chalk. After the ether evaporated, the neutral extract remained in the bottom of the beaker and was a mixture of white and slightly tinted green and yellow crystalline product.…

    • 435 Words
    • 2 Pages
    Good Essays
  • Satisfactory Essays

    Extraction from nutmeg

    • 341 Words
    • 2 Pages

    PURPOSE: The purpose of this experiment was to illustrate the extraction of a solid natural product from its natural source by partition with the aid of an organic solvent. Extraction is the process by which a compound or mixtures of, is transferred by separation from one phase into another. In this case, the major triglyceride contains a single fatty acid identified as myristic acid. It is a substituent of the triglyceride called trimyristin, which embodies 20-25% of the dried weight of ground nutmeg we will eventually use in this experiment. The purpose of this lab is to extract trimyristin from nutmeg with the organic substance, diethyl ether, to evidently produce trimyristin with a small portion of myristicin (solid-liquid extraction). Also, it is good to know that due to impurity the best way purify the product of trimyristin is by recrystallization through hot acetone.…

    • 341 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    The purpose of this experiment is to illustrate how a solid natural product can be extracted from its natural source through the use of an organic solvent.…

    • 682 Words
    • 4 Pages
    Good Essays