MEDICAL SURGICAL (RESPIRATORY)
"ASTHMA BENIFIT OF GERD DRUG TOO SMALL"
It is estimated that more than 75 percent of patients with asthma also experience gastroesophageal reflux disease, also known as GERD (Cleveland Clinic , 2010). Patients with asthma are twice as likely to have GERD. The patients with asthma, who have a severe, chronic form that is resistant to treatment are also most likely to have GERD (K.C.Colgrove, J. Callicoatt,2006). GERD is the backward flow of stomach acid into the esophagus. When acid enters the lower part of the esophagus, it can produce a burning feeling, often referred to as heartburn. If prolonged and untreated, GERD can lead to lung damage, esophageal ulcers and eventually to esophageal cancer ( Saunders Elsevier , 2010). The article was written by Delicia Yard June 21, 2011 and is entitled, “Asthma benefit of GERD drugs too small” The aim of this article is to provide the benefit of a GERD drug to patients with asthma. The article talks about researches that have been done to confirm any asthma benefits of GERD drug such as Proton Pump Inhibitors (PPIs) . Research involves 2,524 patients shows that PPI therapy can result an improvement in morning peak expiratory flow (PEF) rate in adult patients with asthma, but there is not enough improvement for clinical significance (D.Yard, 2011). An article aim on researches presented evidence confirming that relationship between asthma and gastroesophageal reflux disease (GERD) have been established, and as many as 40% to 80% of asthma patients also have GERD ( D. Yard, 2011). The author also talks about the most common treatment, PPI's, which are used for acid reflux. The benefit from this drug against asthma symptoms have been the subject of debate.
An article talks about (unspecified ) meta-analysis of published studies, and results are based on of those studies. First researcher's used...
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