Mutations

Mutations can lead to genetic variations by producing random changes in an organism’s genetic coding. This causes a different protein to be produced, or none at all. Mutation usually has a negative effect due to an important protein and enzyme not being produced, so the organism cannot preform its original function. According to the chart the BRCA1 mutation is more dangerous than the BRCA2 mutation. This is due to the fact the chart shows that a higher percentage of women with the BRCA1 mutation died compared to women with the BRCA2 mutation. The chart shows that 18% of women with breast cancer and a family history of breast cancer die if they have the BRCA1 mutation. While only 2.8% of those same women die if they have the BRCA2 mutation. Heredity and inheritance are in the second chart as all women in the study had a family history of breast cancer.
In order to know the effectiveness of the preventive surgeries you would need to know how many people died after the surgeries, and or the number of people that still had cancer after surgery. This would allow you to compare those who had surgery to those who didn’t.
In the BRCA1 the average age of diagnosis is 44, the average age of diagnosis for BRCA2 is 46, while people with no mutations the average age is 50. With the BRCA1 mutation you are more likely to have cancer at a younger age. With no mutations cancer develops later.
Breast cancer genes are normal genes that have mutated; the surgeries and the deaths remove the mutated genes from the population but don’t prevent other people from developing the mutations