Comp. 2: Academic Research Paper
3 September 2014
Use of Corticosteroid Treatment in Multiple Sclerosis
More than 2.3 million people are diagnosed with Multiple Sclerosis worldwide. There are currently 250,000 to 350,000 people in the United States diagnosed with multiple sclerosis. And about 200 new cases are diagnosed every week (Multiple Sclerosis FAQs). Neurologists prescribe these patients with corticosteroids, either oral or through IV. Although scientists have found no cure to multiple sclerosis, corticosteroids have been used to successfully treat relapses and potentially stop progressive-relapsing and relapsing-remitting multiple sclerosis.
To start off with, multiple sclerosis is a disease of the central nervous system. It damages the protective coating around the nerve fibers that sends messages to all parts of your body controlling muscle and sensory activity. It is an autoimmune disease, this is when your body's own immune system attacks itself. As the damage to protective coating around the nerve fibers increase, it becomes a process known as demyelination where the coating is destroyed. These nerves then become less and less capable at sending messages. As the messages escape they become weaker, leading to difficulty in controlling muscles in different parts of your body. Even when damage occurs to the myelin, it sometimes repairs through internal body repair devices. Described as inflammation at the site of the damage becomes less over time. The rate at which the myelin is damaged is faster than the rate at which repair happens, so the damage becomes more throughout the central nervous system. This damage is known as lesions that take the form of patchy scarring (Managing Your …). Patients and doctors together recognize what the disease does and how it affects your body; still they acknowledge that corticosteroids treat the inflammation and reduce that inflammation.
Furthermore, there are some patterns, anyone can develop multiple sclerosis. More women than men have multiple sclerosis and the percentage keeps increasing as years go by. There is no direct evidence that multiple sclerosis is inherited. Some studies suggest environmental factors, like low Vitamin D have increased the risk of multiple sclerosis. Multiple sclerosis occurs in all ethnic groups, but is most common in Caucasians of European ancestry. When men and women develop multiple sclerosis it usually takes a long time to diagnose. In the early stages of multiple sclerosis, symptoms multiple sclerosis suggest several diseases of the nervous system. Magnetic resonance imaging help give a definite diagnoses since there is no laboratory test available to diagnose multiple sclerosis (Multiple Sclerosis FAQs). As you can see, this means anyone, even if no one in your family has multiple sclerosis, can develop it.
Secondly, there are several different symptoms multiple sclerosis that develop when you have multiple sclerosis. Symptoms multiple sclerosis are different for every person; usual symptoms multiple sclerosis of relapses include optic neuritis, limb weakness, numbness, imbalance, light-headedness, and loss of facial strength. In more serious multiple sclerosis, such as in progressive-relapsing multiple sclerosis, symptoms multiple sclerosis include fatigue, and depression. Relapses usually range from days to weeks and self-fixed around weeks to months. Neurologists use Corticosteroids for selected relapses that have reoccurring symptoms multiple sclerosis and increasingly get worse through-out the relapse. Around fifty percent of neurologists use them for all relapses (Mechanistic Insights…). This states that even patient that have the same type of multiple sclerosis as you, you may have different symptoms multiple sclerosis and be given different treatments for your relapses, dependent on how sever they may be.
Finally, steroids in general are found naturally in plants and...
Cited: Krieger, Stephen, et al. "Mechanistic Insights into Corticosteroids in Multiple Sclerosis: War
Horse or Chameleon?" _Clinical Neurology and Neurosurgery._ 119 (2014): 6-16.
_Multiple Sclerosis FAQs_. National Multiple Sclerosis Society, 2014. Web. 2 September 2014.
Robinson, Ian and F. Clifford Rose "Managing Your Multiple Sclerosis: Practical Advice to
Help You Manage Your Multiple Sclerosis" London: Class, 2004
_Steroids._ Overcoming Multiple Sclerosis, 2014. Web. 2 September 2014.
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