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Multiple Schlerosis Case Study Essay

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Multiple Schlerosis Case Study Essay
Neurobrucellosis In A Patient With Multiple Sclerosis; A Case Report

Abstract

Neurobrucellosis is a rare complication of brucellosis. Acute meningitis and encephalitis are the most common clinical manifestations, however symptoms of these two conditions may be subacute and diagnosis requires a high index of suspicion in patients from endemic areas. Diagnosis is often based on neurological symptoms, serology, and suggestive brain imaging because cerebrospinal fluid culture yields are low.
Herein we report a 30 year old female a known case of MS( Multiple Sclerosis) who presented with ataxia and agitation , in physical examination the patient had ataxic gait and decreased concentration, Brain MRI showed significant brain atrophy and
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Complete blood count (CBC) showed lymph dominant leukocytosis. Wright test in CSF was positive. Accordingly Neurobrucellosis was considered as the cause.
Due to several of immunomodulating or immunosuppressive treatments in the patients with MS, and Chronic suppression of cell-mediated immunity these patients may be more prone to infections. So in such patient careful evaluation of clinical finding are of great
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Utility of the enzyme-linked immunosorbent assay for diagnosing neurobrucellosis, Clin Infect Dis. 1998 Jun;26(6):1481

2-Özisik HI, Ersoy Y, Refik Tevfik M, Kizkin S, Özcan C. Isolated intracranial hypertension: a rare presentation of neurobrucellosis. Microbes and Infection. 2004;6(9):861–863

3-Yilmaz S, Serdaroglu G, Gokben S, Tekgul H. A case of neurobrucellosis presenting with isolated intracranial hypertension. Journal of Child Neurology. 2011;26(10):1316–1318

4-Al-Sous MW, Bohlega S, Al-Kawi MZ, Alwatban J, McLean DR. Neurobrucellosis: clinical and neuroimaging correlation. American Journal of Neuroradiology. 2004;25(3):395–401

5- Ceran N, Turkoglu R, Erdem I, Inan A, Engin D, Tireli H,et al.. Neurobrucellosis: clinical, diagnostic, therapeutic features and outcome. Unusual clinical presentations in an endemic region. Brazilian Journal of Infectious Diseases. 2011;15(1):52–59

6-Seidel G, Pardo CA, David Newman-Toker, Olivi A, Eberhart CG. Neurobrucellosis presenting as leukoencephalopathy. Arch Pathol Lab Med. 2003; 127:e374-377.

. 7-Al-Orainey IA, Laajam MA, Al-Aska AK, Rajapakse CN. Brucella meningitis. J Infect. 1987;

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