morphology of human blood
Morphology of Human Blood and Marrow CELLS
1. Describe two main differences between neutrophilic band and neutrophilic segmented cells.
Peripheral blood of a healthy individual contains 2% to 6% of the band neutrophils. They have a nucleus with a horseshoe or sausage shape they do not have a nucleus separated into lobes connected by a filament. The nuclear chromatin is clumped they stain various shades of pink and contain alkaline phosphatase.
In normal peripheral blood of older adults they have 50% to 70% of segs. The nucleus is separated into two to five usually three lobes connected by a thin filament. Chromatin is clumped and stains purplish-red. Segmentation of the nucleus allows cells to pass through an opening in endothelial lining cells of capillaries and to home in on selected prey such as microorganisms causing disease.
2. Distinguish between eosinophils and basophils
Eosinophils stain reddish-orange mainly composed of major basic protein. The normal adult has 0% to 4% in peripheral blood. Same size or slightly larger than neutrophils. They have a band or two lobed nucleus with condensed chromatin.
Rarely have three lobes.
Basophils 0% to 2 % of normal blood cells they have large abundant violet-blue or purple-black. Granules obscure the nucleus. Granules enable them to be immediately recognized.
3. Four morphological features that are helpful in identifying monocytes
Nuclear convolutions
Lacy delicate chromatin
Dull gray-blue cytoplasm
Blunt pseudopods
4. Four characteristics of lymphocytes
Clumped nucleus
Chromatin condensed
Bluish-red granules are prominent
Cytoplasm has clear non-granular background
1. Describe two main differences between neutrophilic band and neutrophilic segmented cells.
Peripheral blood of a healthy individual contains 2% to 6% of the band neutrophils. They have a nucleus with a horseshoe or sausage shape they do not have a nucleus separated into lobes connected by a filament. The nuclear chromatin is clumped they stain various shades of pink and contain alkaline phosphatase.
In normal peripheral blood of older adults they have 50% to 70% of segs. The nucleus is separated into two to five usually three lobes connected by a thin filament. Chromatin is clumped and stains purplish-red. Segmentation of the nucleus allows cells to pass through an opening in endothelial lining cells of capillaries and to home in on selected prey such as microorganisms causing disease.
2. Distinguish between eosinophils and basophils
Eosinophils stain reddish-orange mainly composed of major basic protein. The normal adult has 0% to 4% in peripheral blood. Same size or slightly larger than neutrophils. They have a band or two lobed nucleus with condensed chromatin.
Rarely have three lobes.
Basophils 0% to 2 % of normal blood cells they have large abundant violet-blue or purple-black. Granules obscure the nucleus. Granules enable them to be immediately recognized.
3. Four morphological features that are helpful in identifying monocytes
Nuclear convolutions
Lacy delicate chromatin
Dull gray-blue cytoplasm
Blunt pseudopods
4. Four characteristics of lymphocytes
Clumped nucleus
Chromatin condensed
Bluish-red granules are prominent
Cytoplasm has clear non-granular background