microelectroonic pill
A new platform of an electronic pill with bidirectional communication system for miniaturized and low power biomedical applications
Nidal Fawaz, Dirk Jansen Institute for Applied Research Offenburg Badstrasse 24, 77652 Offenburg, Germany
Tel.: +49781205128, Email: Fawaz@fh-offenburg.de
Abstract
Electronic pills, smart capsules or miniaturized microsystems swallowed by human beings or animals for various biomedical and diagnostic applications are growing rapidly in the last years. This paper searched out the important existing electronic pills in the market and prototypes in research centers. Further objective of this research is to develop a technology platform with enhanced feature to cover the drawback of most capsules. The designed telemetry unit is a synchronous bidirectional communication block using continuous phase DQPSK of 115 kHz low carrier frequency for inductive data transmission suited for human body energy transfer. The communication system can assist the electronic pill to trigger an actuator for drug delivery, to record temperature, or to measure pH of the body. It consists additionally to a 32bit processor, memory, external peripheries, and detection facility. The complete system is designed to fit small-size mass medical application with low power consumption, size of 7x25mm. The system is designed, simulated and emulated on FPGA.
1. Introduction
Evolution of technology in recent years opened the door for advanced microelectronic systems to be used in medical treatments and diagnostic analysis. Such systems known as smart pills, electronic digestible capsules and intelligent microsystems are rising quickly in this field, they enhance the treatment of several diseases (cancer, diabetes,… ) and carry out biomedical analysis in GI tract (temperature, pH, motility, …), GI diseases affect 60-70 million people annually while
Nidal Fawaz, Dirk Jansen Institute for Applied Research Offenburg Badstrasse 24, 77652 Offenburg, Germany
Tel.: +49781205128, Email: Fawaz@fh-offenburg.de
Abstract
Electronic pills, smart capsules or miniaturized microsystems swallowed by human beings or animals for various biomedical and diagnostic applications are growing rapidly in the last years. This paper searched out the important existing electronic pills in the market and prototypes in research centers. Further objective of this research is to develop a technology platform with enhanced feature to cover the drawback of most capsules. The designed telemetry unit is a synchronous bidirectional communication block using continuous phase DQPSK of 115 kHz low carrier frequency for inductive data transmission suited for human body energy transfer. The communication system can assist the electronic pill to trigger an actuator for drug delivery, to record temperature, or to measure pH of the body. It consists additionally to a 32bit processor, memory, external peripheries, and detection facility. The complete system is designed to fit small-size mass medical application with low power consumption, size of 7x25mm. The system is designed, simulated and emulated on FPGA.
1. Introduction
Evolution of technology in recent years opened the door for advanced microelectronic systems to be used in medical treatments and diagnostic analysis. Such systems known as smart pills, electronic digestible capsules and intelligent microsystems are rising quickly in this field, they enhance the treatment of several diseases (cancer, diabetes,… ) and carry out biomedical analysis in GI tract (temperature, pH, motility, …), GI diseases affect 60-70 million people annually while
References: 3. Meldrom, “pH profile pf gut as measured by radio telemetry capsule” Br. Med. Vol. 2, pp. 104, 1972. 4. Wilding, Hirst, “Development of a new engineering-based capsule for human drug absorptions studies” PSTT vol 3, 2000. 5. Houzego, Patent WO 01/45552 A1, 2001. 18. N. Fawaz, Development of CP-DQPSK Modulator and Demodulator using VHDL for inductive data transmission, Master thesis FH-Offenburg, Germany, 2002. 19. N. Fawaz, D. Jansen, DQPSK Modulator for Inductive Data Transmission, MPC-Workshop, Germany, 2002. 20. Dirk Jansen et. alt.: Electronic Design Automation Handbook, Verlag Kluwer, NL, 2003. 21. C. Eichner, FHOP-Evalboard Technischer Bericht, FH-Offenburg, Germany, 2002. 22. D. Jansen, F. Baier, Induktive bidirektionale Schnittstelle ähnlich ISO/IEC 14443-A, MPC- Workshop, Germany, 2002. 23. D. Jansen, Systematic Design of a Small Processor Core with C-Capability for SOC Designs; Presentation on the colloquium of the CECS, University of California, USA, 2005.