1. How has Merck been able to achieve substantial returns to capital given the large costs and lengthy time to develop a new drug?…
Merck had a 14% increase in sales between 1997 and 1998 and 22% increase in sales from 1998 – 1999, and a 13% annual increase in earnings over the same period. Merck’s business strategy consists of two parts: (1) developing and marketing new drugs through internal research, and (2) developing partnerships with smaller biotechnology companies. Since 1995, Merck had launched 15 new products that earned $5.9 billion on sales of $32.7 billion. Furthermore, Merck may agree to license new drugs from other firms and with its larger capital and greater assets, can assume the risk of submitting the drug through various regulatory approval phases. If the drug becomes profitable, Merck can earn significant cash flows while paying a royalty to the licensor. However, most important is the option that Merck has in deciding when to abandon or continue on this project (deferability or optionality). If Merck reaches a point when its expected NPV is negative, it can simply abandon the project. As a licensee, Merck can allow smaller biotechnology firms to focus on research and development. These smaller firms often have smaller budgets and are not financially or personnel equipped to handle the costly and long FDA approval process, and the subsequent marketing, distribution, and sales of new drugs. This task is better suited for a larger company, such as Merck, which has more resources and money.…
Think about the definition of stakeholders—any parties with a stake in the organizations actions or performance. Who are the stakeholders in this situation? How many can you list? On what basis would you rank them in importance?…
The agreement states Pharmagen will receive up to $500 million funding for R&D costs as they are incurred solely for the research efforts of a potential new drug “X”…
The Opportunity: Merck, a global, research-driven pharmaceutical company, has core values invested in cutting edge science programs. Recently the organization was accosted by Kappa Labs with a proposal to purchase the product KL-798. This drug is associated with obesity and weight-loss which is becoming a valuable investment to the pharmaceutical industry.…
Direct Drugs Inc. (Direct) has created a plan for the acquisition of SolvGen Inc. (SolvGen), which is a publicly owned company. Direct has engaged an audit team to review agreement and procedures dealing with two separate material agreements. The first agreement is a research and development agreement and the second is a licensing and distribution agreement. The contract states that SolvGen entered into a five year research and development agreement with Careway Pharma Inc. on January 1, 2010. The agreement states that SolvGen will use its best efforts to develop a proprietary instrument system. They are expected to be ready for launch in the near future. SolvGen and Careway also entered in an agreement for a five year license and distribution. This agreement was entered in on January 1, 2010 as well. The terms of the research and development agreement state that SolvGen holds all intellectual rights that correspond with the research and development of the contract. Also with this agreement SolvGen is entitled to nonrefundable milestone payments from Careway and they are as follows:…
Sauer, C., & Sauer, R. M. (2007, October). Is It Possible to Have Cheaper Drugs and Preserve the Incentive to Innovate? The Benefits of Privatizing the Drug Approval Process. Journal of Technology Transfer, 32(5), 509-524. doi:http://dx.doi.org/10.1007/s10961-007-9036-0…
The purpose of this paper is to research, analyze and whether to recommend Merck & Co. to potential investors. I will be using both qualitative and quantitative analysis based on previous years of data for the company. I will provide efficient background information (life cycle analysis) including a brief history of Merck & Co., it’s stock chart since being added to the market, any advantages or disadvantages it has within its industry and important news that may affect a potential investor’s willingness to buy or sell this stock.…
The main reason behind PEI investment in providing funding for the research and development for product “X”, is to purchase the rights to receive future royalties from Pharmagen, even if product “X” is not successfully completed and developed. Further, based ASC 730-20-05-3 through 6, Pharmagen has incurred a liability, and has promised to repay this loan using future revenues from either or both product “X” and “Y”, regardless of the outcome of product “X”. There are also no financial risks transferred over to PEI, as they would be paid no matter what the result of product “X”.…
Based on the decision tree model, it is recommended that Pat Harlow does not invest in the purchase of KL-798 from Kappa Labs assuming that the current payoffs and expected probabilities given currently are correct and do not change in the future. At the current decision point, during Phase I tests, there is an expected payoff of -$1.16 million based on the probabilities of success further in the future and expected returns. If Merck can negotiate either the price of KL-798 down by more than $1.16 million or reduce their contribution to complete Phase I testing, this could be an attractive option to invest in.…
While Kenneth Frazier worked liability suits for Merck, he caught the company’s attention and they hired him in 1992. By 1999 Frazier was appointed Merck’s general counsel. Merck saw that Frazier had several good personality traits and values that would benefit their organization.…
Trying to estimate the company’s financial liability from the Vioxx lawsuits would be difficult. From 1999-2004 over 84 million people had taken the drug worldwide. The FDA estimated that 139,000 people in the United States had had heart attacks or strokes as a result of taking Vioxx and 55,000 of those had died. Merrill Lynch estimated the company’s liability for compensatory damages along anywhere from 4-8 billion.…
Underutilization of new effective drugs is a serious concern for pharmaceutical companies. There are many restrictions on pharmaceuticals companies to make their drug available for everyone. Certain restrictions like Medicaid will only allow specific medicine to be reimbursable. If a…
First, note that the $170 million spent are sunk costs, they will be lost regardless of the decision. The relevant question is whether the incremental benefits (the present value of the profits generated from the drug) exceed the incremental costs (the $30 million needed to keep the project alive). Since these costs and benefits span time, it is appropriate to compute the net present value. Here, the net present value of DAS’s R&D initiative is $26,557,759.86…
“May 5, 2005. It was the darkest hour in the pharmaceutical giant 's 114-year history. Merck was drowning in liability suits stemming from Vioxx, its $2.5 billion-a-year arthritis drug, which it had to pull from the market because of a link to heart attacks and strokes. Two other blockbusters worth a combined $7 billion in annual sales were facing patent expirations. And Merck 's labs, which other companies once hailed as a bastion of scientific innovation, were crippled by a culture that buried good ideas under layers of bureaucracy. But in the morass, Clark saw opportunity (www.businessweek.com).”…