Melanosomes move along microtubules by protein motors throughout the cell by aggregation and dispersion and the direction of their traveling is also changed frequently. In microtubules, most kinesins move towards the plus-end of the microtubule, which is called dispersion and dyneins move towards the minus-end of the microtubule, which is called aggregation. (Bouzat, Levi, & Bruno, 2012, p. 1). These dispersion and aggregation of melanosomes are affected by certain hormones such as melatonin and MSH and it make the color of their skin become darker or lighter depending on where they are (Bouzat et al. p. 10).
One significant discovery is that those microtubule- and actin-based transport systems are in a tug-of-war. For instance, microtubule-based transport system can be altered by a loss of myosin function, which is actin-based transport system (Gross et al., 2002, p. 855). This competition regulates their transport functions without a hitch and thus, it allows the movement along microtubules to constantly go on.
Due to traveling of melanophores through those two filaments in