Melanoma
Alexandra Svymbersky
Jessie Powell
English 101
17 DEC 2012
Writer’s Checklist for Cause and Effect Essay
1. Have I identified the cause or effect I am analyzing in my thesis? Yes 2. Have I explained the cause-and-effect relationship convincingly? Yes 3. Have I organized my causes and/or effects logically? Yes 4. Have I used sound logic? Yes 5. Have I concluded my essay effectively? Yes 6. Have I proofread thoroughly? Yes
Alexandra Svymbersky
Jessie Powell
English 101
17 DEC 2012
Melanoma
Melanoma is a type of skin cancer. This is the most serious type of skin cancer. It can form under pre-existing mole. This is why you need to be aware of any lumps or lesions that do not appear to be right. “Cutaneous malignant melanoma falls into two main groups, based on aetiology” (Rees, 2008). The medical name for melanoma actually is melanoma. With this you need to be aware of moles, sores, lumps, and growths on the skin. Any change in appearance of a pigmented skin lesion over time is a warning sign. Also watch for any bleeding from a skin growth. The original descriptions of melanoma of the hand, foot, vulva, and metastatic melanoma to the heart and bowel were by Jean Cruveilhier in his Anatomie Pathologique du Corps Humains published between 1829 and 1842. Cruveilhier 's descriptions predate publications currently ascribed as being the first case reports of these melanomas. “Melanoma development and progression are well defined by clinical and histopathological aspects; however, detailed analysis of molecular changes is still ongoing” (Basserhof, 2005). The development of melanoma is related to sun exposure, particularly to sunburns during childhood and is most common among people with fair skin, blue or green eyes, and red or blond hair. Risk factors for melanoma include: family history of melanoma, red or blond hair and fair skin, presence of multiple birthmarks, development of precancerous lesions, obvious freckling on the
Jessie Powell
English 101
17 DEC 2012
Writer’s Checklist for Cause and Effect Essay
1. Have I identified the cause or effect I am analyzing in my thesis? Yes 2. Have I explained the cause-and-effect relationship convincingly? Yes 3. Have I organized my causes and/or effects logically? Yes 4. Have I used sound logic? Yes 5. Have I concluded my essay effectively? Yes 6. Have I proofread thoroughly? Yes
Alexandra Svymbersky
Jessie Powell
English 101
17 DEC 2012
Melanoma
Melanoma is a type of skin cancer. This is the most serious type of skin cancer. It can form under pre-existing mole. This is why you need to be aware of any lumps or lesions that do not appear to be right. “Cutaneous malignant melanoma falls into two main groups, based on aetiology” (Rees, 2008). The medical name for melanoma actually is melanoma. With this you need to be aware of moles, sores, lumps, and growths on the skin. Any change in appearance of a pigmented skin lesion over time is a warning sign. Also watch for any bleeding from a skin growth. The original descriptions of melanoma of the hand, foot, vulva, and metastatic melanoma to the heart and bowel were by Jean Cruveilhier in his Anatomie Pathologique du Corps Humains published between 1829 and 1842. Cruveilhier 's descriptions predate publications currently ascribed as being the first case reports of these melanomas. “Melanoma development and progression are well defined by clinical and histopathological aspects; however, detailed analysis of molecular changes is still ongoing” (Basserhof, 2005). The development of melanoma is related to sun exposure, particularly to sunburns during childhood and is most common among people with fair skin, blue or green eyes, and red or blond hair. Risk factors for melanoma include: family history of melanoma, red or blond hair and fair skin, presence of multiple birthmarks, development of precancerous lesions, obvious freckling on the
Cited: Reese, Jonathan L. “Melanoma: What Are the Gaps in Our Knowledge.” PLoS Medicine 5.6 (2008): 122-125. Academic Search Premier. Web. 17 Dec. 2012. http://web.ebscohost.com.ezproxy2.apus.edu/ehost/detail?vid=12&sid=669de620-6328-45cb-bb77-3c17b6b66efa%40sessionmgr115&bdata=JnNpdGU9ZQhvc3Qtbl2ZQ%3d%3d#db=aph&AN=32786310 Krauze, Michal, Ahmad Tarhini, Helen Gogas, and John Kirkwood. “Prognostic Significance of Autoimmunity during Treatment of Melanoma with Interferon.” Seminars in Immunopathology 33.4 (2011): 385-91. Academic Search Premier. Web. 17 Dec. 2012. http://web.ebscohost.com.ezproxy2.apus.edu/ehost/detail?vid=15&hid=123&sid=669de620-6328-45cb-bb77-3c17b6b66efa%40sessionmgr115&data=JnNpdGU9ZWhvc3QtbGl2ZQ%ed%ed#db=aph&AN=62867762 Basserhof, Anja-Katrin. "Melanoma Inhibitory Activity (MIA): An Important Molecule in Melanoma Development and Progression." Pigment Cell Research 18.6 (2005): 411-16. Academic Search Premier. Web. 17 Dec. 2012. <http://web.ebscohost.com.ezproxy2.apus.edu/ehost/detail?vid=17&hid=123&sid=669de620-6328-45cb-bb77-3c17b6b66efa%40sessionmgr115&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=aph&AN=18786017>.