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Literature Review
In Vitro Antifungal 1

In Vitro Antifungal Activity of Orthosiphon aristatus (Philippine Taheebo) against Candida albicans

Sheenalyn R. Ching

BS Biology

University of the Philippines Los Banos

In Vitro Antifungal 2

In Vitro Antifungal Activity of Orthosiphon aristatus (Philippine Taheebo) against Candida albicans

Tabebuia impetiginosa is a one of the species of

the well-known medicinal plant, Taheebo. It is common in

Argentina and characterized by clusters of pink, tube-like

flowers arranged in an inflorescence. It is also known as Pink

Lapacho. It reaches a height of 30 meters and usually blooms

between July and September. It has been known to be a remedy

used by the ancient people for various illnesses. This resulted

to various study conducted towards a goal of determining how

vast its medicinal properties are.

Lee, Park, and Yum (2012) studied the anti-

oxidative properties of Taheebo. They used butanol and water to

affect cell survival and tested the effect of Taheebo extract on

these cells.

The three serial extracts were selected for the

study of regeneration on antioxidant enzyme activities because

butanol and water extracts significantly affected cell survival.

Treatment of hydrogen peroxide on the cells showed a dramatic

repression on superoxide dismutase (SOD) and cytosolic NADPH + -

dependent isocitrate dehydrogenase (IDPc) activities with the

remaining activities of 56.1 and 37.5%, respectively. The three

In Vitro Antifungal 3

extracts significantly regenerated SOD activity with the range

of 103 to 178% when compared to the control, and IDPc activity

with the range of 34.4 to 42.2%. The three extracts also

regenerated catalase and glucose-6-phosphate dehydrogenase

activities with the range of 91.6 to 139% in comparison to the

control. Hydrogen peroxide did not change intracellular

glutathione content. The three serial



References: Lee S. U., Park B. S., and Yum J. H. (2012). Antioxidative activity of taheebo (Tabebuia impetiginosa Martius ex DC.) 105 (2006) 255–262. Takusaburo E., Tomoka K. and Naoko O.(2002). ;Antitumor Effect of Hot-Water Extract of TAHEEBO Tea

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