Laboratory Report: Homeostatic Imbalances of the Thyroid Function

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LABORATORY REPORT
Activity:

Homeostatic Imbalances of Thyroid Function

Name:

Miranda Tefft

Instructor:

Aline Potvin

Date:

11.18.2014

Predictions
TSH levels in patients with primary hypothyroidism are high Thyroxine (T4) levels in patients with primary hypothyroidism are low TSH levels in patients with secondary hypothyroidism are low Thyroxine (T4) levels in patients with secondary hypothyroidism are low TSH levels in patients with hyperthyroidism are low Thyroxine (T4) levels in patients with hyperthyroidism are high Materials and Methods
1. Name the Dependent Variable. blood levels of TSH and thyroxine and accumulation of radioactive iodine in thyroid
2. Name the Independent Variable. thyroid activity
3. Name the Controlled Variables. gender, age
4. Why was RIA used to measure Thyroxine while IRMA was used to measure TSH?
RIA is used to measures the thyroxine levels in the blood, while the IRMA measures high or low levels of TSH being released.
5. How was it used to observe relative amount of iodine accumulated by thyroid gland?
RAI measures the amount of iodine that is absorbed by the thyroid. If there is too much it indicates hyperthyroidism, too little indicates hypothyroidism. Results
Table 2. Concentration of Thyroxine and Thyroid Stimulating Hormone (TSH) in Blood Serum
Normal
Thyroxine (mg/l)
TSH (mIU/l)
Type of thyroid disorder 0.05-0.14
0.35-4.5

Patient 1
Value
0.02
7.16

Status
Low
High
Primary
Hypothyroidism

Patient 2
Value
0.01
0.15

Status
Low
Low
Secondary
Hypothyroidism

Patient 3
Value
0.29
0.10

Status
High
Low
Hyperthyroidism

1. The normal range for total amount of Thyroxine in serum is 0.05 - 0.14 mg/L. For each patient, type in their serum Thyroxine concentration and indicate if it is lower, within, or higher than the normal range.
a. Patient with primary hypothyroidism
Lower than normal
Laboratory Report/ Miranda Tefft/ Homeostatic Imbalances of Thyroid Function/ Aline Potvin/ 11.18.2014/ Page [1] of [3]

b. Patient with

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