KAPM And Annotation

The focal event was therefore defined as whichever of these events occurred first (if any occurred). Its elapsed time since the patient was originally diagnosed became the focal event time. If none of these events had (yet) occurred when the patient was last seen the time elapsed between diagnosis and last follow-up alive (or other death) was treated as a censored observation.

The KAPM procedure was invoked to produce a Kaplan-Meier survival analysis.
Annotated outputs of the procedure are shown below and on the next several pages between the horizontal lines. A graphical representation of exactly the same output appears in figure 7 as the corresponding Kaplan-Meier survival curve. Keep in mind, however, that any MR patients who were cured by the intervention would show
a censored observation signifying that a MR patient has been cured by the intervention and, therefore, is no longer at substantial risk of experiencing the focal event, no matter how long observed.

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DESCRIPTIVE SUMMARY OF ELAPSED TIME INTERVALS

The set of strictly positive elapsed observation time intervals relating to 550
PATIENTs constitutes the effective sample for the descriptive summary. There are 401 distinct elapsed time intervals in this set. The complete observation window (i.e., the longest elapsed time interval observed) is 43.0837 elapsed time unit(s). The time unit is one full year.

The MINIMUM number of elapsed time units observed is 0.0821.
The MEDIAN number of elapsed time units observed is 6.5819.
The MAXIMUM number of elapsed time units observed is 43.0837.
The MEAN number of elapsed time units observed is 10.0460, with a STANDARD DEVIATION of 9.1527.

KAPLAN-MEIER ANALYSIS (SURVIVAL RATE ESTIMATED VIA THE PRODUCT-LIMIT