Invasive Aspergillus

Invasive aspergillosis is an infection caused by the fungus of the genus Aspergillus. The fungus immunocompromised individuals due to weakness in defense mechanisms. While it has been largely accepted that Aspergillus species is recognized by cellular receptors and attacked by neutrophils, the radiological and macroscopic findings linking infection with neutropenia remain unconfirmed. However, the fungus survive these attacks and germinate causing the disease. Histopathological changes occurring at the site of infection and altered tissue structures generally result from an extensively complicated interaction between the causative microbes and tissue responses. Methods for diagnosing invasive aspergillosis include serological, imaging and