Homeostasis Lap Report

Powerful Essays
LABORATORY REPORT
Activity:

Homeostatic Imbalances of Thyroid Function

Name:

Theres Castle

Instructor:

Virgil Stoia

Date:

10.20.2014

Predictions
TSH levels in patients with primary hypothyroidism are high Thyroxine (T4) levels in patients with primary hypothyroidism are low TSH levels in patients with secondary hypothyroidism are low Thyroxine (T4) levels in patients with secondary hypothyroidism are low TSH levels in patients with hyperthyroidism are low Thyroxine (T4) levels in patients with hyperthyroidism are high Materials and Methods
1. Name the Dependent Variable. blood levels of TSH and thyroxine and accumulation of radioactive iodine in thyroid
2. Name the Independent Variable. thyroid activity
3. Name the Controlled Variables. gender, age
4. Why was RIA used to measure Thyroxine while IRMA was used to measure TSH?
IRMA is more sensitive than an RIA and is needed to measure the small changes in TSH.
5. How was it used to observe relative amount of iodine accumulated by thyroid gland?
Thyroid imaging was used to observe relative amount of iodine accumulated by thyroid gland

Results
Table 2. Concentration of Thyroxine and Thyroid Stimulating Hormone (TSH) in Blood Serum
Normal
Thyroxine (mg/l)
TSH (mIU/l)
Type of thyroid disorder 0.05-0.14
0.35-4.5

Patient 1
Value
0.01
11.67

Status
Low
High
Primary
Hypothyroidism

Patient 2
Value
0.30
0.09

Status
High
Low
Hyperthyroidism

Patient 3
Value
0.01
0.05

Status
Low
Low
Secondary
Hypothyroidism

1. The normal range for total amount of Thyroxine in serum is 0.05 - 0.14 mg/L. For each patient, type in their serum Thyroxine concentration and indicate if it is lower, within, or higher than the normal range.
a. Patient with primary hypothyroidism lower Laboratory Report/ Theres Castle/ Homeostatic Imbalances of Thyroid Function/ Virgil Stoia/ 10.20.2014/ Page [1] of [3]

b. Patient with secondary hypothyroidism

You May Also Find These Documents Helpful

  • Better Essays

    4. Why was RIA used to measure Thyroxine while IRMA was used to measure TSH?…

    • 1240 Words
    • 7 Pages
    Better Essays
  • Satisfactory Essays

    4. Why was RIA used to measure T4 while IRMA was used to measure TSH?…

    • 515 Words
    • 4 Pages
    Satisfactory Essays
  • Powerful Essays

    Once this occurs it causes the production of the thyroid hormones within the follicular cells which are then released from the thyroid too carry out the necessary functions. However within the patient the T4 levels are very high this causes a negative feedback to the pituitary gland, preventing release of TSH as no more T4 is needed so therefore no more stimulation of the thyroid gland is…

    • 852 Words
    • 4 Pages
    Powerful Essays
  • Good Essays

    Thyroid and Click Submit

    • 1448 Words
    • 6 Pages

    Experiment Results Predict Question: Predict Question 1: Make a prediction about the basal metabolic rate (BMR) of the remaining rats compared with the BMR of the normal rat you just measured. Your answer : b. The hypophysectomized (Hypox) rat's BMR will be higher than the normal rat's BMR. Predict Question 2: What do you think will happen after you inject thyroxine into the three rats? Your answer : c. The hypophysectomized rat will become hyperthryoidic and develop a goiter. Predict Question 3: What do you think will happen after you inject TSH into the three rats? Your answer : a. The normal rat will become hyperthyroidic and develop a goiter. Predict Question 4: Propylthiouracil (PTU) is a drug that inhibits the production of thyroxine by blocking the attachment of iodine to tyrosine residues in the follicle cells of the thyroid gland (iodinated tyrosines are linked together to form thyroxine). What do you think will happen after you inject PTU into the three rats? Your answer : a. The normal rat will become hyperthyroidic and develop a goiter. Stop & Think Questions: 1h. Calculate the oxygen consumption per hour for this rat using the following equation. ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour Enter the oxygen consumption per hour in the field below and then click Submit to display your results in the grid. You answered: 426 ml O2/hr 1i. Now that you have calculated the oxygen consumption per hour for this rat, you can calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the weight data from grams to kilograms to use this equation). Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr Enter the metabolic rate in the field below and then click Submit to display your results in the grid. You answered: 1710.8 ml O2/kg/hr 2h. Calculate the oxygen consumption per hour for this rat using the following equation. ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour Enter the oxygen…

    • 1448 Words
    • 6 Pages
    Good Essays
  • Powerful Essays

    In the titration, I used these available instruments to ensure my results would be as accurate as possible.…

    • 1424 Words
    • 5 Pages
    Powerful Essays
  • Satisfactory Essays

    | How did the metabolic rate of the thyroidectomized rat injected with TSH compare to its baseline metabolic rate? Answer:…

    • 522 Words
    • 3 Pages
    Satisfactory Essays
  • Good Essays

    Look at the data for your assigned challenge. Why did the “guinea pig’s” body react the way it did during the challenge? What was happening inside of the body that you couldn’t necessarily measure or see?…

    • 584 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    To survive, an organism must be able to maintain stable internal conditions in a changing environment. This process is called homeostasis. The Human Homeostasis Gizmo™ allows you to explore how the human body stays at a nearly constant temperature in different conditions. Notice the Air temp. and Body temp. thermometers representing the air temperature and body temperature.…

    • 1077 Words
    • 5 Pages
    Satisfactory Essays
  • Better Essays

    calibration factor (N D,w ), while the TG-21 protocol is based on an exposure ͑or…

    • 3784 Words
    • 16 Pages
    Better Essays
  • Good Essays

    The second method (referred to as "228Ra-LSC" hereafter and the tables and figures) is based on a combined procedure for the determination of 226Ra along with 228Ra and…

    • 978 Words
    • 4 Pages
    Good Essays
  • Satisfactory Essays

    12. My prediction was incorrect. The Tx rat was hypothyroidic, however, it didn't develop a goiter. Its BMR was greater than the normal rat's. This was observed because PTU inhibits thyroxineand the Tx rat cannot produce that on its own because it doesn't have a thyroid gland.…

    • 325 Words
    • 2 Pages
    Satisfactory Essays
  • Satisfactory Essays

    Carbohydrate and Points

    • 614 Words
    • 3 Pages

    8.What was the purpose of using water as a sample in some of the tests performed in the lab? (2 points)…

    • 614 Words
    • 3 Pages
    Satisfactory Essays
  • Satisfactory Essays

    Hlt 362 Exercise 31

    • 436 Words
    • 2 Pages

    6. What is the smallest, significant t ratio listed in Table 2? Provide a rationale for your answer.…

    • 436 Words
    • 2 Pages
    Satisfactory Essays
  • Powerful Essays

    Physio Ex 9.0

    • 781 Words
    • 4 Pages

    The following questions refer to Activity 3: Determining the Effect of TSH on Metabolic Rate.…

    • 781 Words
    • 4 Pages
    Powerful Essays
  • Better Essays

    Hypothyroidism

    • 605 Words
    • 3 Pages

    A goitre can be found in both the underfunctioning as well as the overfunctioning thyroid gland. In the case of an…

    • 605 Words
    • 3 Pages
    Better Essays