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Hashimoto Thyroiditis Essay

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Hashimoto Thyroiditis Essay
Hashimoto’s Thyroiditis is an autoimmune disease of the thyroid gland (1) and is considered to be one of the primary causes of thyroid underactivity, known as hypothyroidism (2). Autoimmune thyroid diseases, like Hashimoto’s Thyroiditis, effects around 1-5% of the population (3, 4), and the large majority of those effected by the disease are women (5). Many aspects of Hashimoto’s Thyroiditis pathology are still being researched, including the determinant and origin of hypothyroidism severity (3).

It has been shown that there are two main influences on development of autoimmune thyroid diseases like Hashimoto’s Thyroiditis. These are environmental factors and genetic sensitivity (4). Environmental factors like dietary iodine intake undertake
…show more content…
Yamada H, Itoh M, Hiratsuka I, Hashimoto S. Circulating microRNAs in autoimmune thyroid diseases. Clinical endocrinology. 2014;81(2):276-81.
4. Tomer Y. Mechanisms of autoimmune thyroid diseases: from genetics to epigenetics. Annual review of pathology. 2014;9:147-56.
5. Merrill SJ, Mu Y. Thyroid autoimmunity as a window to autoimmunity: An explanation for sex differences in the prevalence of thyroid autoimmunity. Journal of theoretical biology. 2015;375:95-100.
6. McGrogan A, Seaman HE, Wright JW, De Vries CS. The incidence of autoimmune thyroid disease: a systematic review of the literature. Clinical endocrinology. 2008;69(5):687-96.
7. Your Thyroid: What You Need to Know. The Journal of Clinical Endocrinology & Metabolism. 2014;99(9):33A-4A.
8. Lin CL, Yang SN, Shiah IS. Acute mania in a patient with hypothyroidism resulting from Hashimoto's Thyroiditis. General hospital psychiatry. 2013;35(6):683 e1-2.
9. Sweeney LB, Stewart C, Gaitonde DY. Thyroiditis: an integrated approach. American family physician. 2014;90(6):389-96.
10. Dorr HG, Bettendorf M, Binder G, Karges B, Kneppo C, Schmidt H, et al. Levothyroxine Treatment of Euthyroid Children with Autoimmune Hashimoto Thyroiditis: Results of a Multicenter, Randomized, Controlled Trial. Hormone research in paediatrics.

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