Guinea Pig Observation
Visiting Sr. Research Scientist May 1998 to Dec 1999 Merck and Co. - West Point, PA
Studied guinea pig’s immune response which produces a very robust T cell response, like humans, against intracellular pathogens. My duties were to develop guinea pig reagents, which are lacking, to do molecular immunological studies in the guinea pig animal model in pre-clinical vaccine development. Performed early development work on vaccines to Haemophilus influenza, Moraxella catarrhalis, and Staphylococcus aureus to elicit an authentic antigenic response. Designed gene-specific PCR primers and PCR amplified the genes; next, performed sequence analysis on all the PCR amplicons and in vitro translated the …show more content…
Instructor for the General Biology lecture and laboratory courses for majors. Co-chair on program and abstracts committee for Science Day activities. I carried out research that investigated the verotoxin receptor’s role in the virulence of Escherichia coli. Developed and implemented a critical thinking problem solving course. Conceived and supervised research for two undergraduates and supervised another in science literature review. Designed and developed a workshop for students going to graduate school. Classes ranged in size from 20-75 …show more content…
Role for verotoxin receptor (Gb3) in B cell adhesion. Presented at the American Society of Microbiology Meeting, Miami, May 1997.
Vines A, Swaminathan B, Schuchat A. Heterogeneity in the structural genes encoding listeriolysin O in three serotypes of Listeria monocytogenes that cause human disease. Presented at the American Society of Microbiology Meeting, Dallas, Texas, May 1991.
Vines A, Reeves MW, Hunter S, Swaminathan B. Restriction fragment length polymorphism in genes associated with virulence in Listeria monocytogenes. Presented at the International Conference Listeria and Food Safety, Laval, France, June 13-14, 1991.
Vines A. Characterization of the phenotype of alkaline phosphates positive marginal zone lymphocytes in mouse spleen. Presented at the 4th Annual Nabrit Biomedical Symposium, Clark Atlanta University, Atlanta, Georgia, 1987.
Vines A. Simultaneous demonstration of alkaline phosphatase and antigen markers in frozen sections. Presented at the 6th Annual Immunology Conference, Toronto, Canada, 1986.
Vines A. The production of monoclonal antibody against P815 tumor cells. Presented at BDSA Spring Symposium, Clark Atlanta University, Atlanta, Georgia,
Studied guinea pig’s immune response which produces a very robust T cell response, like humans, against intracellular pathogens. My duties were to develop guinea pig reagents, which are lacking, to do molecular immunological studies in the guinea pig animal model in pre-clinical vaccine development. Performed early development work on vaccines to Haemophilus influenza, Moraxella catarrhalis, and Staphylococcus aureus to elicit an authentic antigenic response. Designed gene-specific PCR primers and PCR amplified the genes; next, performed sequence analysis on all the PCR amplicons and in vitro translated the …show more content…
Instructor for the General Biology lecture and laboratory courses for majors. Co-chair on program and abstracts committee for Science Day activities. I carried out research that investigated the verotoxin receptor’s role in the virulence of Escherichia coli. Developed and implemented a critical thinking problem solving course. Conceived and supervised research for two undergraduates and supervised another in science literature review. Designed and developed a workshop for students going to graduate school. Classes ranged in size from 20-75 …show more content…
Role for verotoxin receptor (Gb3) in B cell adhesion. Presented at the American Society of Microbiology Meeting, Miami, May 1997.
Vines A, Swaminathan B, Schuchat A. Heterogeneity in the structural genes encoding listeriolysin O in three serotypes of Listeria monocytogenes that cause human disease. Presented at the American Society of Microbiology Meeting, Dallas, Texas, May 1991.
Vines A, Reeves MW, Hunter S, Swaminathan B. Restriction fragment length polymorphism in genes associated with virulence in Listeria monocytogenes. Presented at the International Conference Listeria and Food Safety, Laval, France, June 13-14, 1991.
Vines A. Characterization of the phenotype of alkaline phosphates positive marginal zone lymphocytes in mouse spleen. Presented at the 4th Annual Nabrit Biomedical Symposium, Clark Atlanta University, Atlanta, Georgia, 1987.
Vines A. Simultaneous demonstration of alkaline phosphatase and antigen markers in frozen sections. Presented at the 6th Annual Immunology Conference, Toronto, Canada, 1986.
Vines A. The production of monoclonal antibody against P815 tumor cells. Presented at BDSA Spring Symposium, Clark Atlanta University, Atlanta, Georgia,