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Growth Hormone Deficiency

Growth hormone deficiency is a medical state in which the body generates inadequate amount of growth hormone. This deficiency of growth hormone in children develops dwarfism. For normal growth and development of children, growth hormone is very essential. Children having dwarfism can be treated with replacement therapy of growth hormone (Castro, Rogol, & Shulman, 2011). Somatropin, Humatrope, Genotropin, Saizen, Nutropin, and Norditropin are some drugs which are used as a supplemental growth hormone. Some children having growth hormone resistance can be treated with insulin, for example, growth factor 1 (IGF-1, Increlex). Surgery can be considered as an option for growth hormone deficiency in some cases.
There are supplemental methods present to cope up with the disorder for a time being, but there have been many physical and ethical issues involved in these treatments. Therapies and supplemental treatments have certain side effects: headache; slippage of the bones at the hip; fluid retention; and muscle and joint aches. Supplemental growth hormone treatment looks like an improbable and questionable source of social argument (Buchanan, et. al. 2010).
These therapies primarily cause growth acceleration; it also speeds up teen development and improves bone age so that the interval of growth during teens is summarised. These are typically safe and efficacious intervention (Castro, Rogol, & Shulman, 2011). The main practical



References: Buchanan, K., Batch, J. A., Conwell, L. S., & McMahon, S. K. (2010). Growth hormone deficiency and adrenal insufficiency in a case of primordial dwarfism. In Australasian Paediatric Endocrine Group Annual Scientific Meeting. Castro, L. C., Rogol, A. D., & Shulman, D. I. (2011). Patient information page from The Hormone Foundation. Growth hormone deficiency in children. The Journal of clinical endocrinology and metabolism, 96(12), A35.

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