Fenugreek Research Paper

Trigonella foenum-graecum, generally known as Fenugreek is a species that belongs to the family Fabaceae. Fenugreek has a extensive history dating around 4000 B.C and is located around the Mediterranean region and Asia. The usage of Fenugreek is expansive, the Egyptians consumed fenugreek for nutrition and used it to embalm their dead. The Jews combined fenugreek with boiling oil during war, with the belief that fenugreek would repel the Romans and make them lose their footing. African and Middle Eastern women consumed fenugreek in order to gain weight and promote body growth (https://www.herbs). Even in the 20th century, scientists are still discovering usages for fenugreek. These potential discoveries will be expanded on in this essay. These
Over the past years, there has been an abundant amount of medications that were invented to control obesity but have been withdrawn due to harmful side effects. As of 2016, only one anti-obesity drug is approved by the Food and Drug administration, yet this drug still has intensive gastrointestinal side effects. The discovery to find an anti-obesity drug is needed. To provide evidence that fenugreek could potentially serve as an anti-obesity component to a drug, an experiment on newborn rats was done by Drug Research. Newborn rats were injected with Monosodium glutamate for 4 grams per kilogram from day 2 to day 14 after birth on alternating days. Monosodium glutamate is a manufactured amino acid that is toxic and can lead to diabetes, high blood pressure, and excessive weight gain (http://www.global). On day 43 to 70, each rate was treated orally with an extract of Trigonella foenum-graecum seeds. What was discovered was that during the time period that rats were given the extract of Trigonella foenum-graecum seeds, the rats had restored liver functions and lipogenic enzymes that were close to normal level. As a result, scientists can demonstrate the preventive effect of Trigonella foenum-graecum has on fat deposition and could potentially be a new anti-obesity drug (Kumar et al.,
New tissue will try to replace the scarred tissue which causes the tissue in the lung to become thick and stiff. The tissue in the lung makes it harder for oxygen to go through the walls of the air sac (http://www.lung). To provide evidence that Trigonella foenum-graecum possesses anti-inflammatory property, Chemico-Biological Interactions conducted a research. The experiment involved using glycosides based standardized fenugreek seed extract (SFSE-G) and evaluate the interaction with bleomycin (BLM) in laboratory rats. Each rat group was induced to idiopathic pulmonary fibrosis by a single injection, followed by either SFSE-G in different quantities (5, 10, 20, or 40 milligrams per kilogram), or methylprednisolone (10 milligrams per kilogram) and then observed after 14 and 28 days of the drug treatment. The results of this experiment were that glycosides based standardized fenugreek seed extract (SFSE-G) administered in 20 and 40 milligrams per kilograms both showed the prevention of bleomycin alterations in body weight, lung function, and others. There was an increase in peripheral blood oxygen after glycosides based standardized fenugreek seed extract was used. Not only that but there was a reduction in lung 5-HT level by this treatment. Apoptosis, or the death of a cell controlled to the growth and development of a system were significant. All of these results provide evidence to suggest that