Effects of Nicotine on Brain

Topics: Dopamine, Nicotine / Pages: 17 (4120 words) / Published: Feb 3rd, 2013
A Meta Analysis: Nicotine’s effects on the Neurological Disorders of Obsessive Compulsive Disorder, Attention Hyperactive Activity Disorder, Schizophrenia Abstract Nicotine has been shown to affect the disorders of OCD, ADHD and schizophrenia. A study has not been conducted to determine if previously collected data is significant enough to have nicotine used as a treatment for these disorders. Research was conducted through accessible literature to collect data of tests performed on patients with these disorders. T-tests were done on the data for all three of the disorders to determine if the application of nicotine is a significant treatment plan. The results show that nicotine has statistically significant efficacy for reducing specific symptoms across all three disorders. Most t-tests showed that there were significant improvements between the patient’s preliminary test scores and their post-treatment scores. These results show that nicotine use should be a more common treatment plan for three disorders, since it has proven to be effective, and in some trials has shown to be more effective than the currently used treatments for the disorders. Introduction
Nicotine, a chemical substance derived from the tobacco plant, alters neurological function once consumed by the human body. Nicotine plays a large role in mimicking the neurotransmitter dopamine once inside of the brain and deals with memory, cognition, perception, and a wide variety of primary functions associated with the frontal lobe of the cerebral cortex (Livingstone et al., 2009). It provides a state of heightened neural activity due to more excitatory neurotransmitters present within synaptic clefts of neurons. This extra molecular presence within the synaptic gaps can lead to stabilizing and more homeostatic dopamine-like concentrations within the brain that could potentially lead to the alteration of cognitive deficits associated with neurological diseases linked to altered dopamine levels



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