ANTIHYPERTENSIVE DRUGS: 3 OVERVIEW: 3 HYPERTENSION: 3 CLASSIFICATION OF BLOOD PRESSURE: 4 REGULATION OF BLOOD PRESSURE: 5 SITES AND EFFECTS OF ANTIHYPERTENSIVE DRUGS: 6 DIURETICS: 6 CENTRALLY ACTING DRUGS: 10 ANGIOTENSIN INHIBITORS: 11 SPECIFIC DRUGS: 14 ANGIOTENSIN RECEPTORS BLOCKERS: 14 DIRECT RENIN INHIBITOR: 15 VASODILATORS: 15 CALCIUM CHANNEL BLOCKERS: 15 OTHER VASODILATORS: 16
ANTI ANGINAL DRUGS: 16 MECHANISM AND EFFECTS OF ANTIANGINAL DRUGS: 17 TYPICAL ANGINA: 18 VARIANT ANGINA: 18 EFFICACY OF DRUG USED IN TREATMENT OF CORONARY HEART DISEASES 20 TYPICAL ANGINA PECTORIS 20 ANTI ISCHEMIC AGENTS 20 PREVENTIVE AGENTS 20 VASODILATORS: 20 CALCIUM CHANNEL BLOCKERS: 22 ADRENOCEPTOR ANTAGONISTS: 25 MANAGEMENT OF ANGINA PECRORIS: 26
DRUGS FOR HEART FAILURE: 27 OVERVIEW: 27 PATHOPHYSIOLOGY OF HEART FAILURE: 28 MECHANISM AND EFFECT OF DRUG FOR HEART FAILURE: 29
A n estimated 50 million people in the united states have high blood pressure (hypertension) , commonly defined as a sustained systolic blood pressure of 140 mm hg or higher or a sustained diastolic pressure of 90 mm of hg or higher . Numerous studies have shown that untreated high blood pressure damages blood vessels, accelerates atherosclerosis, and produces left ventricular hypertrophy. The rate at which these changes occur is proportional to the severity of hypertension. Eventually, these abnormalities contributes to the development of ischemic heart disease, stroke, heart failure and renal failure , which are the most common cause of death in patients who are hypertensive.
Over the past several decades, health professionals and public officials have increased their efforts to educate the public about the hazards of untreated hypertension and this has led to a significant increase in a number of hypertensive individuals who are aware of their conditions and treat it