Drug Study

Topics: Chemotherapy, Cancer, Cell cycle Pages: 3 (756 words) Published: December 17, 2010
Drug study

Sangobion: Anti emetic

Indications : Anemia
Moa: It replenishes iron stores in the body and corrects hemoglobin deficit by increasing hemoglobin levels
A/E: GI upset
NC: Administer with meals, teach client breathing techniques, monitor hemoglobin count.

Domepridone : Motillium (anti dopamionergic)

Indications: patient has gastric tube
Moa: Stimulates gastrointestinal by acting as a competitive antagonist at dopamine D2 receptor, inhibits gastrointestinal motility, reduces gastric and esophageal sphincter. A/E: dizziness, constipation, leg cramps

NC: administer before meal, stay with client , observe for signs of A/E

Metoclopromide: ( Anti emetic)

Indication: Gatric tube
Moa: Dopamine antagonist that acts by increasing sensitivity to acetylcholine, results in increase motility of the upper GI tract and relay action of the pyloric sphincter and duodenal bulb. A/E: Restlessness, drowsiness, fatigue, nausea , headache

NC: Stay with the patient, Monitor for fluid replacement incase of vomiting, Secure patients safety.


is a drug that is a pyrimidine analog which is used in the treatment of cancer. It works through noncompetitive inhibition of thymidylate synthase. Due to its noncompetitive nature and effects on thymidine synthesis, 5-FU is frequently referred to as the "suicide inactivator". It belongs to the family of drugs called antimetabolites. It is typically administered with leucovorin.

Moa: As a pyrimidine analogue, it is transformed inside the cell into different cytotoxic metabolites which are then incorporated into DNA and RNA, finally inducing cell cycle arrest and apoptosis by inhibiting the cell's ability to synthesize DNA. It is an S-phase specific drug and only active during certain cell cycles. In addition to being incorporated in DNA and RNA, the drug has been shown to inhibit the activity of the exosome complex, an exoribonuclease complex of which the activity is essential for cell...
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