denaturation

Topics: Protein, Amino acid, DNA Pages: 2 (343 words) Published: September 26, 2013
Denaturation (biochemistry)
Denaturation is the alteration of a protein shape through some form of external stress (for example, by applying heat, acid or alkali), in such a way that it will no longer be able to carry out its cellular function. See also:

Plants & Animals
Cell Biology
Genetics
Molecular Biology
Matter & Energy
Biochemistry
Organic Chemistry
Thermodynamics
Denatured proteins can exhibit a wide range of characteristics, from loss of solubility to communal aggregation. Proteins are very long strands of amino acids linked together in specific sequences. A protein is created by ribosomes that "read" codons in the gene and assemble the requisite amino acid combination from the genetic instruction, in a process known as translation. The newly created protein strand then undergoes post-translational modification in which additional atoms or molecules are added, for example copper, zinc, iron. Once this post-translational modification process has been completed, the protein begins to fold (spontaneously, and sometimes with enzymatic assistance), curling up on itself so that hydrophobic elements of the protein are buried deep inside the structure and hydrophilic elements end up on the outside. The final shape of a protein determines how it interacts with its environment. For more information about the topic Denaturation (biochemistry), read the full article at Wikipedia.org, or see the following related articles: Protein folding — Protein folding is the process by which a protein structure assumes its functional shape or conformation. All protein molecules are heterogeneous ... > read more Protein structure — Proteins, similar to carbohydrates and lipids, are made up of such elements as carbon, hydrogen and oxygen. They are amino acid chains, made up from ... > read more Protein biosynthesis — Protein biosynthesis (Synthesis) is the process in which cells build proteins. The term is sometimes used to refer only to protein translation but ... >...
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