Congenital Myasthenic Syndrome

The common cause of congenital myasthenic syndromes is genetics, affecting the junction where the nerve triggers muscle activity. The inherited autosomal recessive gene exists in both parents, who pass the mutated gene to the offspring. The syndrome appears shortly after birth or early childhood. Severity ranges from minor to increasing concentrations of muscle weakness.
There are over twenty different genes known to cause congenital myasthenic syndromes, as different as each individual. Sometimes the conditions occurs randomly without any family history or illness connected to the disorder.
Families with a history of this condition have a higher risk of passing the inherited trait to their child. Although parents may not show signs of the