Compound Nerve Action Potentials
A functional neuron carries important information through action potential, this is significant activity of the neurons to allow us to understand abnormality in the nerve that cause disorders. The objective of this study was to trigger a compound nerve action potentials (CAPs) and examine the effects of a stimulus voltage on a nerve and inspect their threshold, refractory period and also their velocity. Compound nerve action potentials (CAPs) are summed action potential of one nerve, one nerve consists of many neurons. We used the sciatic Lithobates pipiens nerve in this experiment, the sciatic nerve is long nerve, it extends from the buttocks to the legs. it is connected to these areas, it sends an electric signals and impulses to and from
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Figure 1 showed that the elicited compound nerve action potentials (CAPs) of the Lithobates pipiens nerve showed progressive increase in amplitude with each increase in stimulus intensity going from 20mv to 40 mv to 60mv etc. demonstrating that not all neurons have reached their limits aka threshold. We could say that the amplitude for each neuron doesn't increase with the stimulus intensity but increases because more neutrons are firing and reaching their threshold at each point. Figure 2 also showed that the amplitude decreased in response to stimulus interval. The amplitude showed a significant decrease and complete disappearance at 2.5ms (figure 2) that’s the end of relative refractory period. In relative refractory period, there can be few Na+ channel open but not enough to reach the threshold and cause all or nothing response. When the amplitude reached zero, that would be the absolute refractory period. In this period there can be no Na+ channel open and it can not be stimulated in this period. Table 1 the determination of conduction velocity of Lithobates pipiens nerve was found to be 4.75 m/s which is pretty low range, could be due to an error. Neurons give off an electrical signal that allow neurons to communicate with each other to deliver information very quickly. The point of this experiment was to look at the relationship between the levels of …show more content…
The same can be said when it is in refractory period, the sum of all neurons firing. The nerve in that region have sensory and motor neurons that are in charge of that muscle, this nerve is called the sciatic nerve. It allows movement in particularly jumping to the frog. If the nerve is damaged, it may lead to muscle weakness and numbness. One of the clinical applications that neurons can be used is in Vagus nerve stimulation (VNS) which is the new treatment/therapy used for those have have hard to treat epilepsy, VNS treatment has appeared to decrease epileptic seizures in both the intensity and in number in patients that seem unresponsive to anti-epileptic drugs. It also has its utility in both neuropsychiatric disorders and in mental illness as well. (Beekwilder, J. P. and T. Beems,
Figure 1 showed that the elicited compound nerve action potentials (CAPs) of the Lithobates pipiens nerve showed progressive increase in amplitude with each increase in stimulus intensity going from 20mv to 40 mv to 60mv etc. demonstrating that not all neurons have reached their limits aka threshold. We could say that the amplitude for each neuron doesn't increase with the stimulus intensity but increases because more neutrons are firing and reaching their threshold at each point. Figure 2 also showed that the amplitude decreased in response to stimulus interval. The amplitude showed a significant decrease and complete disappearance at 2.5ms (figure 2) that’s the end of relative refractory period. In relative refractory period, there can be few Na+ channel open but not enough to reach the threshold and cause all or nothing response. When the amplitude reached zero, that would be the absolute refractory period. In this period there can be no Na+ channel open and it can not be stimulated in this period. Table 1 the determination of conduction velocity of Lithobates pipiens nerve was found to be 4.75 m/s which is pretty low range, could be due to an error. Neurons give off an electrical signal that allow neurons to communicate with each other to deliver information very quickly. The point of this experiment was to look at the relationship between the levels of …show more content…
The same can be said when it is in refractory period, the sum of all neurons firing. The nerve in that region have sensory and motor neurons that are in charge of that muscle, this nerve is called the sciatic nerve. It allows movement in particularly jumping to the frog. If the nerve is damaged, it may lead to muscle weakness and numbness. One of the clinical applications that neurons can be used is in Vagus nerve stimulation (VNS) which is the new treatment/therapy used for those have have hard to treat epilepsy, VNS treatment has appeared to decrease epileptic seizures in both the intensity and in number in patients that seem unresponsive to anti-epileptic drugs. It also has its utility in both neuropsychiatric disorders and in mental illness as well. (Beekwilder, J. P. and T. Beems,